• Immune System Tricked to Accept Mismatched Donor Organs

    A group of scientists have found a method for deceiving the immune system so that it will accept organs from an incompatible donor, a finding that could help patients avoid a lifetime of medication to prevent rejection of the organ. The procedure involves suppressing the patient’s bone marrow with chemotherapy and radiation before they undergo surgery;...

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  • Early Surgery for Refractory Epilepsy Improves Quality of Life

    Patients with drug-resistant temporal lobe epilepsy may benefit from surgical intervention soon after failure of two antiepileptic drug (AED) trials, according to results of the Early Randomized Surgical Epilepsy Trial (ERSET).       Surgery is usually seen as a last resort, but researchers have concluded that earlier intervention could help epilepsy...

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  • Shortage of ICU Beds Leads to Patient Deaths

    A lacking supply of ICU beds is leading to preventable deaths, according to a study from France. Dr. Rene Robert of Hopital Jean Bernard in Poitiers, France and colleagues found that out of 1,332 patients referred to ICUs in those hospitals over a three-month period, almost 15% were turned away, at least temporarily, because there were no beds available....

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  • The Future of Non-Invasive Ventilation

    Introduction Non-invasive ventilation (NIV) provides safe and effective assistance to patients with acute respiratory failure (ARF) from various causes (Garpestad et al. 2007). The main reason for applying NIV is to avoid the complications of endotracheal intubation, according to Evans et al. (2000). The ventilator setting generally used to apply...

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  • Decreasing Central Line Associated Bacteraemia in a New Zealand Intensive Care Unit

    Putting Evidence into Practice Introduction Central venous catheters are commonly used in intensive care units, with studies suggesting that approximately 50% of ICU patients have such lines inserted. Meanwhile, central line infections are responsible for 40-60% of bloodstream infections in intensive care patients, according to New South Wales...

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  • An Emerging Consensus for Acute Kidney Injury

    Acute kidney injury (AKI) is a hot topic in the medical arena, with prominent research and discussion ongoing, prompting amendments to recommended practice. The Acute Kidney Injury Network (AKIN) and Acute Dialysis Quality Initiative (ADQI) and AKI section of the European Society Intensive Care Medicine (ESICM) continue to work on counsel for clinical...

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  • Improving handovers by learning from Scuderia Ferrari

    Introduction It has been nearly a decade since seminal reports and associated research documenting the surprising frequency of accidental injury in healthcare were published in the UK and around the world (Vincent, Neale and Woloshynowych 2001). Around that time, complex and systemic causes of a sequence of probable accidental deaths at the Bristol...

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  • Past and Present Challenges in ICU Management

    Introduction Maintaining an intensive care unit (ICU) and providing intensive care for all patients who benefit from it necessitates a high investment in personnel, technology, and material resources within a short time period, and is naturally associated with costs. The complexity of the care processes involved, and the fluctuation in the...

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  • The Perfect ICU

    A disheartening moment in any medical department, particularly in the critical arena, is that of unforeseen human error leading to injury. With teams doing their utmost to ensure the best chances of survival for patients, the inevitability of occasional mistakes occurring in what is an immensely complex system is a distressing concept to shoulder....

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  • The Intensive Care Unit of Tomorrow: A Case Study of Patient-Centred Care

    The University Medical Center Utrecht (UMC Utrecht) is a 1,042 bed hospital, which admits approximately 30,000 inpatients per year. All academic specialties are present and the hospital provides a core service in heart and lung transplantations, ventricular assist devices, trauma, neurosurgery, oncology, haematology and AIDS patients. In 2004,...

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