• Healthcare-Associated Bacterial Infection: Common Sources of Severe Sepsis Among People with HIV

    Authors Jared A. Greenberg, MD Section of Pulmonary and Critical Care Medicine Department of Medicine, University of Chicago Chicago, US [email protected]   John P. Kress, MD Section of Pulmonary and Critical Care Medicine Department of Medicine,...

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  • Polytrauma and Organ Crosstalk

    Authors Dieter G. Weber, MBBS, FRACS Department of Traumatology, Division of Surgery John Hunter Hospital and University of Newcastle Newcastle NSW, Australia Zsolt J. Balogh,   MD, PhD, FRACS, FACS Department of Traumatology, Division of Surgery John Hunter Hospital and University of Newcastle Newcastle,NSW, Australia [email protected]...

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  • How to Understand Organ-Organ Interactions

    A Compartment Syndrome (CS) is Defined as Increased Pressure in a Closed anatomic space which threatens the viability of enclosed and surrounding tissue (Malbrain et al. 2006). Within the body there are four major compartments: the head, the chest, the abdomen and the extremities. Within each compartment, individual organs can be affected...

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  • The Future of Glucose Control in the ICU

    Continuous glucose monitoring systems and therapeutic algorithms adapted to the actual insulin sensitivity are needed to prevent hypoglycaemia, hyperglycaemia and high glucose variability, all associated with poor outcome in intensive care unit (ICU) patients....

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  • Nutritional Failure: An Adaptive Response to Critical Illness?

    For decades, intensive care unit (ICU) physicians have been administering artificial nutrition to improve recovery and outcome. This intensified nutritional support has been associated with a better outcome in several large observational studies (Alberda et al. 2009), though unfortunately, it is impossible to distinguish cause and consequence by association....

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  • West Nile Virus Encephalitis: Recognising and Diagnosing Infection

    The increasing spread of West Nile virus (WNV) infection is worrying and requires that all intensivists be ready to recognise and diagnose the disease. Most individuals infected with WNV are asymptomatic, while one-fifth experience a flu-like illness and less than 1% develop neuroinvasive disease. Introduction West Nile...

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  • Valuing Prevention as the New Paradigm in Global Health

    Managing Population Immunity for Vaccine Preventable Diseases One lesson from progress towards polio eradication suggests that using models and measurements together to manage population immunity may play a key role in supporting the paradigm shift required to value prevention and realise...

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  • Challenges and Changes in Mexico After the Influenza AH1N1 Outbreak

    From Standard ICU to Tele Presence with Robotics and Tele-Ultrasound From March to December 2009, the Influenza AH1N1 outbreak was observed in several cities of Mexico, showing deep flaws in the healthcare system and a general lack of knowledge on how to act and react in case of an epidemic. Because of that, thousands of people...

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  • Challenges in Critical Care in Africa: Perspectives and Solutions

    Critical care medicine in Africa is largely an unknown entity in the medical world, though it has recently begun to emerge as a prominent concern, mostly due to increasing research that has highlighted the plight of this sub-specialty in Africa (Adhikari et al., 2010, Riviello et al., 2011). However, the fact that critical care medicine is considered...

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  • Therapeutic Hypothermia in the ICU: Indication, Sedation and Prognostication

    Mild therapeutic hypothermia (TH) applied for 24 hours in the intensive care unit (ICU) is now recommended in comatose survivors of an outof- hospital cardiac arrest (OHCA), though some uncertainty around indication, clinical management and prognostication still remains. We will probably see this exciting field of intensive care further evolve...

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