HY-RiSE® is designed for checking the cleanliness of surfaces by detecting organic impurities in the form of product residues even on surfaces considered clean after visual inspection. This kit does not require the use of an analytical instrument. HY-RiSE® measures nicotinamide adenine dinucleotides (NAD, NADH) and their phosphates. These compounds are found in all living cells, including microorganisms, as well as in food and food debris. Color development on the test strip indicates a positive result and thus that the tested surface is not clean. The detection of biological residues invisible upon visual inspection enables timely re-cleaning. Cleaning processes are improved in a controllable manner.