SmartFAST laboratory cabinet ensures high containment reliability, providing a class ISO 3 working area highly protected from both air-born contaminants and no-hazordous micro-organisms . Compact, economic and easy-to-place new concept of laminar flow cabinet, gives two working possibilities: Overpressure system: part of the sterile air is exhausted through the front opening. Depression system: part of the filtered air is exhausted, while air from outside is partially brought in through the front opening thus obtaining a protective barrier. To exchange the two operational systems, it is sufficient to change the position of the closing plate on the top of the cabinet.