The novel, innovative Tissue-Tek® Paraform® Cassette System eliminates the need to perform manual steps at the embedding centre. Using Tissue-Tek® Paraform® in combination with the Tissue-Tek® AutoTEC® Automated Embedder allows the automation of the time consuming, manual process of embedding. The unique Tissue-Tek® Paraform® Cassette System consists of an outer frame that is compatible with all commercially available cassette printers and microtome chucks, and an inner cassette, which is made of Paraform® material. The cassette preserves the orientation of the tissue sample from grossing through sectioning, eliminating the risk of orientation errors or losing tissue samples. A unique feature of Paraform® is that it is easy to section, just like paraffin wax. The Paraform® Cassette is compatible with all existing laboratory methods and manual embedding processes. In addition, it can accommodate a variety of specimens, even those requiring special orientation (e.g. skin or arterial specimens), in one of the six available cassette types: Standard, Biopsy, Biopsy 13 x 13, Shaved Biopsy, Core Biopsyand Orientation.