Fluid and Vasopressor Decisions in Early...
- Sepsis
- 30/04/2024
Latest Articles in Sepsis
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Biomarkers in Sepsis - Present and Future
A biomarker defines a measurable indicator of a patient's medical situation that can be measured precisely and accurately. Biomarkers provide value for diagnosis, prognosis, early disease detection, risk stratification, suitable treatment (theragnostic), and trial improvement for patients with sepsis or presumed sepsis. Introduction...
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Sepsis Diagnosis: Clinical Signs, Scores, and Biomarkers
Abstract Sepsis and antimicrobial resistance are two major public health problems . Sepsis is defined as a dysregulated response of the body to a bacterial infection with organ dysfunction . The 2021 Surviving Sepsis Campaign SSC guidelines proposed characterising the infection based on clinical assessment and the dysregulated...
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Imaging the Critically Ill
Imaging is integral to managing critically ill patients in the ICU as it is a key source of diagnostic information to guide clinical decision-making. In recent years, there has been significant evolution in the field of critical care imaging with an increased focus on improving imaging modalities and methodologies and increasing access to imaging...
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The Clinical Utility of Estimated Plasma Volume in Critical Care
An overview of clinical evidence that demonstrates the prognostic value of estimated plasma volume (ePVS) in critically ill patients. Relevance Plasma volume (PV) is the total volume of blood plasma – the extracellular fluid volume of the vascular space. It is associated with regulating interstitial and intravascular spaces; hence it can...
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Guiding Clinical Care Using Pancreatic Stone Protein
The role of point-of-care testing in the early identification and management of sepsis, the need for better markers to identify sepsis, an overview of the Pancreatic Stone Protein (PSP) and clinical evidence highlighting its effectiveness as a biomarker. Pancreatic Stone Protein Infections are a leading cause of morbidity and mortality...
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Sepsis in Critical Care
The importance of clearly defining sepsis, improving early recognition strategy, and increasing the understanding of innate and adaptive immune system derangements that facilitate the development of sepsis. The improvement in mortality outcomes of patients with sepsis is attributable to the early recognition of sepsis, better adherence to guidelines,...
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Pancreatic Stone Protein Biomarker for Sepsis, Antimicrobial Resistance and Nosocomial Infections
The problem of antimicrobial resistance and the use of a clinical decision score and point-of-care testing biomarkers, such as CRP and PSP, to help solve this problem. Introduction Infectious diseases are a public health issue around the world, with bacterial, viral, parasitic, or fungal-related diseases responsible for 26% of mortality...
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Practical Implementation of the Pancreatic Stone Protein Sepsis Test
An overview of a discussion on sepsis and the Pancreatic Stone Protein (PSP) biomarker by Dr João Pereira, Hospital De Vila Franca De Xira, Portugal and how it can be used for early diagnosis of sepsis and facilitate decision-making regarding the administration of antibiotics. The discussion was chaired by Prof Pedro Póvoa, coordinator of...
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Sepsis in Critical Care
Sepsis is a leading cause of morbidity and mortality in the intensive care unit. Nearly 14 million adults and 2.5 million children survive sepsis each year worldwide. In addition, sepsis survivors are known to experience poor long-term outcomes and often develop functional limitations thereafter. It is thus evident that the long-term impact...
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One Sepsis Fits All? Are There Different Phenotypes of Sepsis? Diagnostic Approaches and Therapies
This article presents current research results in relation to an advanced sepsis classification and their implications for new treatment options and research strategies. Introduction Through history, the definiti on and the term sepsis changed. Since Semmelweis and others formulated the thesis that sepsis was caused by a systemic reaction...
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Latest News
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Unravelling the Role of HIF-1α in Sepsis
- Sepsis
- 02/04/2024
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Vascular Leak in Sepsis
- Sepsis
- 26/03/2024
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