Latest Articles in icu
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Fluid Resuscitation in Burns
What Is New? Following a severe burn injury, an overwhelming systemic inflammatory response with capillary leak syndrome is initiated, resulting in a combined hypovolaemic and septic shock (Malbrain et al. 2014a). Numerous articles regarding burn resuscitation have been published over the last decades; however, there is no universal consensus on...
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Critically Ill Diabetic Patients
The Case for Liberal Glycaemic Management Background Several large randomised controlled trials (RCTs) have helped provide evidence to guide clinicians’ decisions about blood glucose management in critically ill patients. In two landmark single centre studies, investigators from Leuven reported a reduction in mortality or morbidity with tight...
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Heart-Lung Interactions from the Lung's Perspective
In this article we describe the characteristics of the interaction between lung protective ventilation and pulmonary and right ventricular function in ARDS. We highlight and discuss the concept that protective ventilation should be directed towards all components of the functional unit, and discuss how mechanical ventilation can modulate the interaction...
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Infections in the Immunosuppressed and Immunocompromised Patient
Over the last decades the number of immunocompromised patients has increased in parallel with improvements in transplantation science and alongside the development of numerous new classes of immunosuppressive agents offering novel therapy for a wide range of diseases. For example, an estimated 114,690 solid organ transplants were performed globally...
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Clinical Benefits of Rapid Pathogen Testing with PCR/ESI-MS
Dr. Mark Wilks, Clinical Scientist, Microbiology at Barts Health NHS Trust in London, UK, talks about their experiences of using PCR/ESI-MS technology over a period of 18 months. During its use for the RADICAL study, the department also ran clinical samples of interest through the technology. Which patient groups could potentially benefit...
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Book Review: The Organization of Critical Care
There are not many good books on this topic, and the present one includes contributions from North American and Australian experts in the field. The book has three main sections: organisation, improvement and integration, and a shorter fourth section on global and future perspectives. The list of topics is quite comprehensive, from ICU practitioners...
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The Brain
Treatment of neurological illnesses and complications in the intensive care unit remains a challenge. And as intensivists we are aware of the risks of cognitive impairment for many ICU patients. For our cover story this issue we address practical brain matters. Nino Stochetti explains how to choose fluids for brain injured patients to achieve the...
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Critical Care Medicine in Korea
The Past, The Present and the Future History of Critical Care in Korea and the Korean Society of Critical Care Medicine The first intensive care unit (ICU) in Korea was established in 1968 with six beds in a university hospital in Seoul, and the number has since expanded to 220 ICUs taking care of 3197 patients (data from a one-day survey in 2009)....
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Reducing the Risk of Recurrence of C. Diff Infection
A study published in JAMA has shown that drinking a non-toxic strain of Clostridium difficile bacteria could help reduce the incidence of recurrent infection caused by the toxic strains of the bacteria. C. difficile is the most common cause of healthcare-associated infection in U.S. hospitals, and recurrence occurs in 25 to 30 percent of patients....
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