Latest Articles in icu
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Precision Medicine in Sepsis
Multiple failed clinical trials testing immunomodulatory therapies for sepsis argue for a new approach. While precision medicine has been successfully implemented in other fields, testing it in sepsis poses challenges, which this review will discuss, along with potential implementation strategies. Sepsis has an estimated annual incidence of 1.3...
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ARDS and Precision Medicine
What is the path forward for treatment of acute respiratory distress syndrome (ARDS)? Is it big trials (favoured by clinical scientists) or further insight into disease physiopathology (favoured by basic scientists)? Or both? Funding resources are limited and the debate is wide open. In the post-genomic era, a new direction is needed. On 20 January 2015,...
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The Power of Listening: Engaging the Consumer
Darryl O’Callaghan and Julie Vermeir are survivors of a road trauma that happened in 2010. Their article provides insight into their journey as patient and wife, and the lessons that can be learnt. Darryl’s Story There are many courageous souls who have lost their lives attempting to climb Mt Everest. Those who attempt such a climb arrive...
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Improving Healthcare: The Role of the Human Factors Specialist
What is human factors? How would you explain to a hospital director why they should hire human factors specialists? Human Factors (HF) is the study of how people interact physically and psychologically with their environment—this includes the products, tools, procedures and processes they interact with. HF professionals use insights...
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elisa 800 VIT – Bedside VALI and VILI Detection
Mechanical ventilation has become the established standard therapy for acute respiratory failure in modern intensive-care medicine. Although intensive-care ventilation frequently represents the only option to ensure sufficient pulmonary gas exchange and adequate tissue oxygenation, ventilation therapy can also cause further lung damage and lead to ventilation-induced...
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Quality Management: The Role of Intensive Care Registries
To initiate, maintain and advance a quality improvement programme in your intensive care unit consumes large amounts of time and energy. There are many advantages for quality management in joining an intensive care registry; the most important is access to precisely defined data for comparative audit. Intensive Care Registries Joint...
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Biomarkers in Heart Failure
Cardiac biomarkers, including natriuretic peptides and troponins, have become widely used in the treatment of heart failure and acute coronary syndrome. As we learn more about the function of these markers, their use has begun to expand. We can now track and utilise natriuretic peptides throughout hospital admission to monitor progress of heart failure...
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Learning to Lead an ICU: New Course
A course for aspiring and practising intensive care unit (ICU) leaders will take place in Brussels in January 2017. ICU Management & Practice spoke to some of the faculty, which includes Editor-in-Chief, Prof. Jean-Louis Vincent, to find out more. Who is the course for? This course will attract participants...
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Renal Replacement Therapy for Acute Kidney Injury: Questions Remain
Eric Hoste is Professor in Medicine and Head of Clinic at Ghent University Hospital, Belgium. Prof. Hoste’s primary clinical area of interest is clinical critical care nephrology, and he has published more than 190 original papers, review articles and book chapters primarily within this field. He is a Senior Clinical Investigator, Research Foundation-Flanders...
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Does Dexmedetomidine Reduce Delirium by Improving Sleep?
Delirium is a common complication in intensive care unit (ICU) patients and its occurrence is associated with worse outcome (Inouye et al. 2014; Abelha et al. 2013). Sleep disturbances are considered one of the important risk factors of delirium development (Flink et al. 2012). Recent evidence shows that dexmedetomidine, either at sedative or non-sedative...
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