Cook Biotech Incorporated (CBI), located in the Purdue Research Park in West Lafayette, Indiana, was established in 1995 following a Purdue University biomedical engineering research team's discovery of the unique properties of porcine small intestinal submucosa. Since the company was founded, CBI has developed and currently manufactures advanced tissue repair products for worldwide distribution.Cook Biotech's products are based on extracellular matrix (ECM) technology. The source for the ECM is derived from porcine small intestine and is known to have unique tissue remodeling benefits.Using a variety of surgical procedures, the grafts are placed to repair or reinforce damaged tissue. Once in place, the graft provides a scaffold-like structure that allows the body to restore itself. Over time, the graft is remodeled into fully vascularized tissue and becomes as strong as the patient's own tissue.