The Thermo Scientific Cryotome FSE Cyrostat is a fifth generation machine which has been altered to adapt to multiple samples and users. It is design to offer comfort to the user. It has a decreased amount of turnaround time and responds to temperature quickly. It features a chamber that is spacious and easy to clean. It boasts colored cryocassettes and a superb knife holding design. This enables the user identify frozen sections quickly. The Thermo Scientific Cryotome FSE Cryostat features a microtome located on the outside of the cyrochamber which makes it easier to clean.