SelectBag Citrate is a unique citrate-containing, acetate-free concentrate developed by Gambro for regular hemodialysis and hemodiafiltration treatments. Citrate is a natural metabolite providing both buffering capacity and energy to the patient. Citrate is also a well-known antioxidant and anticoagulant. Coagulation activation and oxidative stress lead to increased inflammation, and are identified risk factors for developing cardiovascular disease in dialysis patients. It is a safe and biocompatible alternative to acetate allowing Individualized Quality-assured Dialysis (IQD). The benefits for patients include improved acid-base status, easier electrolyte individualization, decreased thrombogenic dialysis, reduced inflammation, and improved tolerance to treatment.