The Nephral ST hydrogel membrane has a symmetrical structure that improves diffusion, convection and its other adsorptive properties. It also helps in removing b2-microglobunlin, AGEs, cytokines or anaphylatoxins efficiently. Treating the membrane's surface with PEI biopolymer stops blood contact activation. It also binds heparin upon priming with a solution that is pre-heparinized. This can result into lesser heparin administered to the patient. Furthermore, in association with Acetate-Free Biofiltration therapies, the Nephral ST dialyzer helps patients gain cardiovascular stability.