The Foundation of a Successful Implant In 1971, Stryker Simplex P Bone Cement revolutionized orthopaedics. Two years later, the product was approved for total knee surgery, and in 1976 for use in pathological fractures and general prosthetic fixation. In 2003, Simplex P with Tobramycin became one of the first cleared antibiotic-impregnated bone cement in the United States. Simplex P SpeedSet, a faster-setting version of Stryker’s original formula, was released in 2006. For more than 40 years, Simplex P Bone Cement, combined with the Stryker cement delivery system, has earned the trust and confidence of tens of thousands of surgeons. Countless articles in respected, peer-reviewed journals confirm its performance.1-3