The new FDX Series is the most innovative product released by Nikkiso and it aims to provide the most natural treatment through FDX and FDY dialyzers generation. The impressive blood purification feature is its most attractive feature followed by excellent endotoxin retention properties. Endotoxins and bacteria are blocked through a full-proof, triple safety system mechanism. The system involves blocking of bacterial contaminations, endotoxins and their fragments in the dialysate-sided skin layer, adsorption in the middle layer and additionally holding back by the thin skin layer on the capillary side.There is very low albumin loss through this system. The triple system is also used in the dialysate filters of the EF series. the system provides high efficiency high-flux hemodialyzers for HD, HDF and HF with 30 µm PEPA membrane and also the asymmetrical 3-layer structure.