This system has been designed for optimized versatility along with an easy, reproducible technique of implantation. It accommodates both constrained applications, in which the screws are rigidly locked to the plate, and semi-constrained constructs, which allow motion of the screws with respect to the plate. These fixation approaches allow the surgeon to use the most applicable technique when treating a variety of traumatic and non-traumatic cervical (C2-T1) spine pathologies. This device is not approved for screw attachment to the posterior elements (pedicles) or the cervical, thoracic, or lumbar spine.