MRI Predicts Cognitive Outcome in Preterm Children
Researchers say that early identification of preterm children at risk for future impairment using brain markers would assist clinicians in directing families to targeted early intervention. For this study, the researchers assessed up to 224 preterm children at age five and age seven using MRI. The study participants are from Melbourne, Australia and are part of a Murdoch Children's Research Institute study.
The investigators were looking for associations between diffusion MRI and local brain volumes on neonatal MRI with number skills and working memory in childhood. They found that neonatal brain microstructure was positively associated with working memory scores in childhood. In addition, increasing tissue volumes in the left insula and putamen regions of the neonatal Jacobian map were positively associated with higher number skills scores in childhood.
"Our findings demonstrate that brain microstructure and increased tissue volumes in regions located around the insula and putamen during the neonatal period are associated with better early mathematics in preterm children," says the study's co-author Henrik Ullman, who is affiliated with the Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Co-author Megan Spencer-Smith, also from Karolinska Institutet, adds, "This knowledge could assist in identifying infants at risk of mild academic impairments who would benefit from monitoring and referral to early intervention. Such an approach could assist in reducing the number of preterm children performing below their peers in mathematics."
This research also suggests that identifying these children early could reduce behavioural and emotional problems in childhood, as well as reducing wellbeing and mental health problems in adulthood.
Source and image credit: Oxford University Press
Published on : Mon, 7 Sep 2015
We recognize that the best chance any patient has at getting better is a clinician at their bedside with all the right answers and the confidence to act. SonoSite education and training is the industry standard – no other point-of-care ultrasound manufacturer...
BioZorb® 3D Bioabsorbable Marker The BioZorb® is a 3D implantable marker that consists of a spiral, bioabsorbable framework embedded with 6 permanent, titanium clips designed to precisely mark your surgical excision site. Designed to improve outcomes...
UltraDrape is an innovative dressing designed for use during Ultrasound-Guided Peripheral Intravenous (UGPIV) that provides dual-action barrier and securement in one.
The iViz is a lightweight Point Of Care (POC) ultrasound solution, specifically designed for emerging sub-segments where there is need for a highly accessible and mobile solution that is capable throughout key areas of the patient care path. The iViz...
A better 3D™ breast screening experience – for everyone. The new 3Dimensions™ system is designed to provide higher quality 3D™ images for radiologists, a more comfortable mammography experience for patients and enhanced workflow for technologists....