Obstructive Sleep Apnea Raises Risk of Sudden Cardiac Death, Mayo Clinic Finds
In the study, funded by the NHLBI, 10,701 people who participated in sleep studies were followed for an average of 5.3 years for incidence of sudden cardiac death. In that time, 142 patients died of sudden cardiac death. The most common predictors were an age of 60 or older, 20 or more apnea episodes per hour of sleep, and an oxygen saturation below 78 percent during sleep.
"What we found that is new with this study is that if you have sleep apnea, your risk of sudden death increases almost twofold, particularly if you stopped breathing more than 20 times per hour of sleep and if you had severe falls in oxygen saturation during sleep," says senior author Virend Somers, M.D., Ph.D., a Mayo Clinic cardiologist.
When a person is breathing properly, the oxygen saturation level — when air flows through the lungs — during sleep is 100 percent, Dr. Somers says. This study showed that if a person is not breathing properly and the oxygen saturation level falls to as low as 78 percent, the risk of sudden cardiac death significantly increases, he says.
Lead author Apoor Gami, M.D., says Mayo Clinic's previous research showed that people with sleep apnea have a much higher risk of sudden cardiac death between midnight and 6 a.m., when people are typically asleep, while people without sleep apnea die more often from sudden cardiac death between 6 a.m. and noon.
"So we knew that sleep apnea changed the time of sudden cardiac death, but we didn't know if it changed the overall risk," Dr. Gami says. "This new study shows that sleep apnea does indeed increase the overall risk of sudden cardiac death independently of other important risk factors.
"The prevalence of obstructive sleep apnea in Western populations is high, and because of the relationship between weight and sleep apnea, the current obesity epidemic is going to further increase the scope of this problem," noted Dr. Gami, formerly at Mayo Clinic and now a cardiologist at Midwest Heart Specialists-Advocate Medical Group in Elmhurst, Ill.
Research has shown that sleep apnea is potentially an important cause of cardiovascular conditions, such as high blood pressure, atrial fibrillation, heart attacks and strokes, Dr. Somers says. Sleep apnea is treatable. In addition to weight loss, physicians also can recommend sleep posture changes and devices, such as a machine that delivers air pressure through a mask placed over the nose while a person sleeps, he says.
Source: Mayo Clinic
Published on : Fri, 14 Jun 2013
Print as PDF
The technical and clinical reference standard for all B·R·A·H·M·S PCT assays. All clinical cut-offs and algorithms were developed based on B·R·A·H·M·S PCT sensitive KRYPTOR. Homogeneous immunoassay for the quantitative d
The HAMILTON-C1 neo is a versatile neonatal ventilator that combines invasive and noninvasive modes with the additional options of nCPAP and high flow oxygen therapy. The integrated turbine allows it to be operated independently of a compressed air supply....
17 critical parameters from a blood sample as small as 45 µL Not available in the US When the sample is small but your diagnostic needs are big, the ABL90 FLEX PLUS blood gas analyzer provides critical insights with a turnaround time of less than...
Medos hemofilters pro are used for efficient and gentle hemofiltration during extracorporal circulation.Medos hemofilters pro do not need to be pre-flushed and can be used immediately. This guarantees a safe and quick hemofiltration.
Patient Dedicated Arterial Blood Gas Analyzer Frequent measurement of arterial blood samples is an important component in the effective management of patients in the critical care environment, particularly those that are unstable. Point of care or...