The topic of hydroxychloroquine is particularly hot for two reasons: the first is that the drug is cheap, can be obtained quite easily, and seems “safe” because it has been widely used for many years in the prevention of malaria. The second reason is that its administration was promoted by Professor Didier Raoult, an internationally recognised expert who can be very convincing when he appears on screen. However, his clinical data are unconvincing: the “famous” study included only 26 patients and had serious methodological problems, the principal one being exclusion from analysis of six patients in the treated group who did not improve. Current recommendations are, therefore, to reserve administration of hydroxychloroquine in the hospital to severely ill patients receiving cardiac monitoring.
COVID-19: From Hydroxychloroquine to Plasma Administration
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Published on : Wed, 1 Apr 2020
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