• Pharmacokinetic/Pharmacodynamic Principles to Combat Antimicrobial Resistance

    Pharmacodynamic and pharmacokinetic principles play a central role in antimicrobial dose-optimisation to combat antimicrobial resistance. In the future, research focused on the integration of preclinical and clinical data is paramount. Antimicrobial Resistance in the ICU The use of antimicrobial drugs in the hospital is very common...

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  • Antibiotic Stewardship in Critical and Emergency Care

    An overview of antimicrobial stewardship in critical care units and emergency departments, highlighting aspects to reduce multidrug resistance focusing on antibiotic optimisation in respiratory infections and sepsis. Introduction Infections caused by resistant bacteria are associated with higher treatment costs and increased morbidity...

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  • Multidrug-Resistant Gram-Negative Bacteria in the ICU

    Severe infections by antibiotic resistant gram-negative bacteria are frequent in ICU patients. They are associated with high morbidity and mortality. Introduction Bacterial infections in patients hospitalised in the Intensive Care Unit (ICU) are frequent, and they elicit an increase in morbidity and mortality. The emerging development...

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  • Rapid Diagnostics and Antimicrobial Resistance in the ICU

    The need to address the problem of antimicrobial resistance, the importance of faster diagnosis of bacterial infections and an overview of rapid diagnostic testing. Antimicrobial resistance (AMR) is rapidly increasing on a global scale. The discovery of penicillin revolutionised the field of medicine, providing safe harbour from the most...

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  • Pancreatic Stone Protein Biomarker for Sepsis, Antimicrobial Resistance and Nosocomial Infections

    The problem of antimicrobial resistance and the use of a clinical decision score and point-of-care testing biomarkers, such as CRP and PSP, to help solve this problem.  Introduction  Infectious diseases are a public health issue around the world, with bacterial, viral, parasitic, or fungal-related diseases responsible for 26% of mortality...

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  • Improving Clinical Outcomes With Early Enteral Nutrition

    An overview of the benefits of early enteral nutrition, clinical evidence and recommendations, reasons for delayed enteral feeding in critically ill patients and optimal solutions. Early enteral nutrition is proven to improve clinical outcomes and reduce acute care costs. Nutrition clinicians support the belief that enteral nutrition is...

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  • Short Acting Beta-Blockers in Critically Ill Patients With Heart Failure

    An overview of the clinical evidence demonstrating the effectiveness of landiolol for the treatment of atrial fibrillation or atrial flutter with heart failure and effective heart rate control during arrhythmias.   Supraventricular arrhythmias (SVTs) are common in post-operative and cardiac ICUs. SVTs increase the risk of death...

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  • Antibiotic Resistance

    Antibiotic resistance is one of the most significant public health challenges today. Join our panellists as they discuss the problem of antibiotic resistance, its impact on patient outcomes, the importance of effective antimicrobial stewardship programmes, the role of rapid diagnostic testing, and important strategies to reduce the spread of antimicrobial...

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    ACEP 2023 - American College of Emergency Physicians

    ACEP 2023 - American College of Emergency Physicians

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    Optimised Prediction of All-Cause Mortality of ICU Patients

    • ICU
    • 11/10/2022

    Outcomes research on ICU patients requires accurate measures of comorbidity to predict mortality. The Simplified Acute Physiology Score (SAPS3) is...

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