• Multiple organ support

    Interventions intended to support one organ can have unexpected implications on the patient, presenting physicians with critical decisions. These can be aided with innovative technologies and new techniques, but only if well understood. We often come across multiple organ dysfunction syndrome (MODS), with incremental degrees of physiologic derangements...

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  • Out with the saline?

    Reduced use linked to better outcomes Two companion studies have shown that use of saline as intravenous fluid therapy, compared to crystalloids, was associated with poor survival and increased risk of kidney complications. Matthew Semler, MD, MSc, assistant professor of Medicine at Vanderbilt University School of Medicine, told ICU Management...

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  • ICU delirium a distinct indicator of acute brain injury

    More than half of ICU patients in a new study experienced delirium for long periods during their stay. Sedative-associated delirium was most common, while longer periods of hypoxic delirium and unclassified delirium were associated with worse cognitive function at follow-up one year after hospital discharge. You might also like : Sedative prevents...

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  • CO2 in the critically ill

    CO 2 exerts potent effects on lung biology that could be clinically relevant in critically ill patients, in particular those with acute respiratory distress syndrome (ARDS). The impact of hypercapnia on outcome in these patients is yet to be determined. The physiological effects of hypercapnia are increasingly well understood, but the literature...

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  • Improving diagnostic stewardship by using new microbiological technologies

    Describes an episode of sepsis in a leukaemia patient, whose treatment was early guided by using rapid diagnostics technology to identify the cause of infection. A 4-year-old patient under treatment for acute lymphoblastic leukaemia, diagnosed 6 months before, was admitted to the emergency room (ER) at midnight (00h33) due to a fever episode...

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  • Immune dysfunction in sepsis

    An overview of the recent advances in the diagnosis and treatment of immune system dysfunction in sepsis. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection (Singer et al. 2016). Sepsis-induced immune system dysfunction is an important sequelae of sepsis. The persistence of immune system dysfunction...

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  • Variation in end-of-life care

    Do we need yet another standard operating procedure? Variability in end-of-life care would seem to demand a standard operating procedure, but a roadmap towards harmonisation arguably would be easier to implement. Mainly due to enormous pharmacological and technological innovation during the last decades, intensive care medicine can...

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  • “Simulate, or not to simulate?”

    Evolution in medicine and the anaesthesia context. A brief discussion about the importance and the state of the art of simulation in anaesthesia and intensive care medicine. Training in simulation plays a key role in complex systems such as aviation and the nuclear industry, to investigate predictable errors that lead to adverse outcomes....

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  • Upcoming events

    APRIL 5-7 14th Emirates Critical Care Conference Dubai, UAE https://iii.hm/hud 12-14 ESICM EuroAsia 2018 Hong Kong https://iii.hm/hue 12-15 14th WINFOCUS World Congress on Ultrasound in Emergency & Critical Care Madrid, Spain https://iii.hm/huf 26-27 15th Annual Critical Care Symposium Manchester, UK...

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  • Gut microbes protect against sepsis

    New research published in Cell Host & Microbe suggests that gut bacteria may help in the fight against sepsis. In the study, mice were given particular microbes, which increased blood levels of immunoglobulin A (IgA) antibodies, protecting the mice against polymicrobial sepsis. You might also like : Study: Microbiome Disruption May Have Key Role...

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