• Can Goal-Directed Therapy solve the economic burden of postsurgical complications?

    How effective are less invasive or even noninvasive methods?   The clinical and economic burden of post-surgical complications and the economic impact of Goal-Directed Fluid Therapy (GDFT) implementation.     Improving the quality of care by reducing post-surgical complications, decreasing mortality, and decreasing hospital...

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  • PICU Up! A multicomponent early mobility intervention for critically ill children

    An overview of the 'PICU Up!' mobility programme at Johns Hopkins Children's Center, which integrates sleep promotion, delirium prevention, and sedation optimisation to increase mobilisation in critically ill children.   What is the PICU Up! Programme?   Paediatric intensive units traditionally have had a culture where critically ill children...

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  • Infographic

    Caring for the critically ill child  

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  • PICU-acquired complications: the new marker of the quality of care

    This article describes the rise in PICU-acquired morbidities and its impact on patient outcomes. It discusses early rehabilitation strategies to improve patient outcomes in PICU.  Introduction Critical care has traditionally been focused on early recognition of life-threatening conditions, resuscitation, and stabilisation of organ...

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  • A structural approach for diagnosing weaning failure

    A case from a specialised weaning centre Using a case of a former patient we describe the structured approach of analysis of the cause of weaning failure with corresponding specific therapies used in our Centre for Expertise. Previously, we suggested a structural approach for diagnosing the cause of weaning failure (Heunks and van...

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  • Vitamin D deficiency in ICU patients

    A review on the role of vitamin D in a well-defined setting of critically ill patients: patients undergoing cardiac surgery and organ transplantation, and the potential benefit of vitamin D supplementation.   Vitamin D research has experienced a true hype in all fields of medicine in the last decades. In critical illness, this increased...

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  • Noise in the intensive care unit: where does it come from and what can you do about it?

    Practical measures and interventions to reduce noise levels in the ICU and to improve the patient experience. The intensive care unit (ICU) is known to be noisy and is getting louder (Busch-Vishniac et al. 2007). Despite several trials, no interventions have been able to reduce noise levels by a meaningful amount (Li et al. 2011; Boyko...

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  • Big Data and hidden subtypes of sepsis

    Results of a study conducted by the University of Pittsburgh School of Medicine suggests that sepsis is not one condition, but many conditions that could benefit from different treatments. The findings are published in JAMA and were presented at the American Thoracic Society's Annual Meeting.   Sepsis is the number one killer of hospitalised patients...

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  • Sedation with dexmedetomidine in critically ill patients

    Dexmedetomidine is used to sedate patients while maintaining a certain degree of sustainability. The use of dexmedetomidine is known to reduce the duration of mechanical ventilation and delirium among patients in the intensive care unit (ICU). However, its use as the sole sedative agent in patients undergoing mechanical ventilation has not been studied...

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  • Use of opioids in the ICU not linked to continued prescriptions

    According to a new study, opioids prescribed in the intensive care unit (ICU) do not drive risks for continued use or prescriptions. The findings were presented at the American Thoracic Society (ATS) 2019 International Meeting in Dallas, TX.   Opiate abuse is a major healthcare issue. In the U.S., opioid-related deaths have increased more than three-fold...

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