Surge Mechanical Ventilation During COVID-19

2022 09 Aug

During the COVID-19 pandemic, many hospitals in the U.S. exceeded their mechanical ventilation capability. As COVID-19 spread to communities with limited immunity, challenges associated with providing surge mechanical ventilation were reported. Hospitals, healthcare systems, and jurisdictional authorities purchased more ventilators. But the fear that the... Read more

The Influence of COVID-19 on Intensivist Wellbeing

2022 09 Aug

The COVID-19 pandemic has been challenging for healthcare systems around the world. In particular, the pandemic has resulted in critical care staffing shortages and has affected the quality of care.  In this review, the researchers examine the emergency response of hospitals to the pandemic and how it influenced the well-being of frontline intensivists.... Read more

Capnodynamic Monitoring to Assess PEEP in COVID-19

2022 02 Aug

Optimal positive end-expiratory pressure (PEEP) level during mechanical ventilation for COVID-19 pneumonia remains debated. A third of experts in a recent consensus statement supported a low-level PEEP for COVID-19-related acute respiratory failure (C-ARDS), with half of the panel remaining neutral without agreement on PEEP titration. However, the... Read more

Neurologic Manifestations of COVID-19

2022 19 Jul

Approximately 10-15% of patients with COVID-19 require ICU treatment. Respiratory failure and multi-organ dysfunction are the most common indications for ICU admission. However, nearly 1/3 of COVID-19 patients also present with neurologic manifestations. Neurologic manifestations are believed to predict mortality and functional outcome. While there... Read more

Extended Prone Positioning for COVID-19 ARDS

2022 12 Jul

COVID-19 has resulted in an estimated 270,000 hospitalisations in ICUs in Europe between May 2020 and March 2022. Nearly 80% of these patients have required tracheal intubation and invasive mechanical ventilation. While there is still an ongoing debate whether acute respiratory distress syndrome (ARDS) physiopathology is the same in COVID-19 and non-COVID-19... Read more

Response to PEEP in COVID-19 ARDS With & Without ECMO

2022 05 Jul

There have been conflicting results concerning lung recruitability of COVID-19 acute respiratory distress syndrome (ARDS) and the use of techniques derived from changes in respiratory mechanics and/or gas exchange in response to positive end-expiratory pressure (PEEP) increase. Various factors may explain the heterogeneity of reports regarding recruitability... Read more

COVID-19 Vaccines Prevented 20 Million Deaths Worldwide

2022 28 Jun

Findings from the first modelling study to quantify the impact of COVID-19 vaccines show that nearly 19.9 million out of a potential 31.4 million deaths were prevented in the first year (December 2020-December 2021) after the introduction of the vaccine. The findings are based on data from 185 countries using COVID-19 death records and total excess... Read more

Early Deep Sedation in Mechanically Ventilated COVID-19 Patients

2022 20 Jun

Sedation management is a critical component when managing mechanically ventilated patients. It is important to use a protocol-driven approach, which favours paired spontaneous awakening (SAT) and breathing (SBT) trials, along with light levels of sedation. The initial period of respiratory failure in the emergency department and the first 48 hours... Read more

#EA22: Long-Term Exposure to Air Pollution Increases Risk of Severe COVID-19

2022 07 Jun

New research presented at Euroanaesthesia 2022 finds that long-term exposure to air pollution is linked to a greater risk of severe COVID-19. Findings from the study show that people living in counties with higher levels of nitrogen dioxide (NO 2 ) were more likely to need ICU care and mechanical ventilation if they had COVID-19. Long-term exposure... Read more

Clinical, Organisational Factors and COVID-19 Mortality

2022 31 May

Coronavirus disease 2019 (COVID-19) is one of the most significant challenges faced by critical care workers worldwide. During the COVID-19 pandemic, an unprecedented number of patients with COVID-19 associated pneumonia were admitted to the ICU. As a result, most healthcare facilities faced capacity issues and had to designate clinical areas to accommodate... Read more

Long COVID and Recovery Following Hospitalisation

2022 10 May

More than 500 million cases of COVID-19 have been reported worldwide. Patients infected with COVID-19 are at a higher risk of persisting health impairments six months after hospital discharge associated with reduced physical function and health and quality of life. It is thus important to understand the long-term trajectory of recovery from COVID-19.... Read more

Effect of Prone Position C-ARDS

2022 27 Apr

COVID-19 has resulted in the death of over 4 million people worldwide. In severe cases of COVID-19, acute respiratory infection leads to severe pneumonia, which worries to progress hypoxaemia and acute respiratory distress syndrome (ARDS).  Prolonged sessions in the prone position is an effective intervention to decrease mortality in these patients.... Read more

VA-LRTI Infections in COVID-19

2022 19 Apr

COVID-19 continues to create a strain on healthcare systems around the world. Approximately 10-30% of COVID-19 patients admitted to the hospital need ICUs, and 15-20% of these patients require ventilatory support. The available data shows an increased risk of ventilator-associated pneumonia (VAP) and ventilator-associated lower respiratory tract infections... Read more

ICU-Related Loss of Quality of Life After COVID-19

2022 12 Apr

COVID-19 has had a significant impact on the number of hospital admissions, including many patients presenting acute respiratory failure. Approximately 15% of hospitalised COVID-19 patients require ICU admission.  It is well established that the physical and psychological impact of an ICU stay on patients can be quite significant and prolonged.... Read more

#ISICEM22: The Place of Antiplatelet Agents in COVID-19 (REMAP-CAP Trial)

2022 22 Mar

Thrombotic events are common in patients hospitalised with COVID-19. Platelet activation has been implicated in the COVID-19 inflammatory response. However, the efficacy of antiplatelet therapy in critically ill patients with COVID-19 is still uncertain.  The Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia... Read more

Awake Prone Positioning for Non-Intubated COVID-19 Patients

2022 22 Mar

Prone positioning can improve oxygenation and mortality for intubated patients with moderate to severe acute respiratory distress syndrome (ARDS). Prone positioning of non-intubated patients called awake prone positioning has been used for non-intubated patients with COVID-19 related acute hypoxaemic respiratory failure. It has been proven to improve... Read more

Drug Dosing Recommendations for Obese COVID-19 Patients

2022 21 Mar

Obesity is highly prevalent in patients who are hospitalised with COVID-19. It is a widely recognised risk factor for severe COVID-19 infection with a greater risk for mortality compared with non-obese patients. With each 1 kg/m 2 increase in body mass index, the risk for severe infection increases by 9% and mortality by 6%.  While there are... Read more

ICU Management of the Very Old: The Evidence Base Anno 2022

2022 16 Mar

This overview explores the publications concerning the very old ICU patients since 2011 and with a focus on publications from the VIP network on elderly COVID-19 patients. Introduction In 2017, an international group of intensivists with a particular interest for geriatric intensive care published a statement paper (Flaatten et al.... Read more

Burnout Syndrome Among Critical Care Clinicians

2022 08 Mar

COVID-19 was declared a pandemic by the World Health Organization (WHO) in March 2020. Since then, nearly 100 million patients have been infected worldwide, and millions of deaths have been reported.  While healthcare systems overall have been under immense pressure around the world, critical care teams, in particular, have shouldered significant... Read more

Findings from the COVID-VENT Trial

2022 08 Mar

Many patients with COVID-19-associated acute respiratory failure fulfil the criteria of acute respiratory distress syndrome (ARDS) and require invasive mechanical ventilation. Therefore, it is important to understand the features of gas exchange abnormalities, respiratory mechanics and lung recruitability in these patients to provide an appropriate... Read more