• From Hydroxychloroquine and Remdesivir to Plasma Administration

    Clinicians are faced with a serious disease with no effective therapy. Several options are being considered to treat COVID-19, but how promising are these drugs? A  number of colleagues and friends from outside the hospital have asked me whether they should take hydroxychloroquine for their COVID-19. A friend asked me whether he should...

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  • An Adaptive Response to COVID-19

    John Nosta is the founder of NostaLab, a digital health think tank. He is regarded as one of the top global strategic and creative thinkers in digital health. He's also a member of the Google Health Advisory Board and a technology expert for the WHO. John is a contrarian with a sharp focus on the future, and it is this quality that makes him a defining...

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  • The Calm Before the Storm

    Preparing intensive care capacity for the COVID-19 pandemic at a tertiary hospital in South Africa. Introduction The COVID-19 pandemic caused by the novel severe acute respiratory syndrome Coronavirus-2 (SARS-Cov-2) has wrought havoc on hospitals throughout the world. As of 25th April 2020, the burden of disease in South Africa remains...

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  • COVID-19: Masks in Intensive Care Units

    With the number of COVID-19 cases increasing in the intensive care units, there is a high risk of infection for healthcare professionals. What kind of masks can be used and what are the most effective strategies to protect against airborne particles? C urrently, there is an increasing number of patients in the intensive care units...

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  • COVID-19 and the History of Pandemics

    How are we dealing with the COVID-19 pandemic and the lessons we can learn from similar diseases over the last few centuries. The face of human history has always been pockmarked by disease, in more ways than one. In our current privileged world of technology, gene sequencing and micro RNA, the possibility of a new disease that kept us inside...

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  • What COVID-19 Has Taught Me…

    A personal narrative of Adrian Wong’s experience while battling COVID-19 at King’s College Hospital. These are the author’s personal opinions and do not represent the views of the institution and professional societies to which they belong. T he global COVID-19 pandemic has changed healthcare throughout the world and the specialty of...

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  • Thoughts on COVID-19 from the International Fluid Academy

    An overview of what has been published on fluid strategies in COVID-19, guidelines available and reflections on personal practice. Introduction The global COVID-19 pandemic has sharply focused the attention of the world onto critical care as a specialty. At the moment, there are no proven treatments for COVID-19, although several trials...

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  • Feasibility and Potential Benefits of Immersive Virtual Reality in the Intensive Care Unit

    Virtual reality (VR) is a developing technology with much current interest in its potential to improve patient outcome in a variety of clinical settings. Critically ill patients, their relatives and intensive care unit (ICU) staff are all at high risk of stress and anxiety and patients often experience pain. This study explores the potential benefits...

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  • Vasoactive Agent Management for Haemodynamic Support in COVID-19 Patients

    An overview of the Surviving Sepsis Guidelines for the vasoactive agent management of COVID-19 patients with septic shock and the use of arginine vasopressin in this patient population. The SARS-CoV-2 has caused a global health crisis. Thousands of people across the globe have been affected by COVID-19. Clinicians are in urgent need of...

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  • Noninvasive Haemodynamic Check to Guide Educated Decisions in the Management of COVID-19 Patients

    The rapid global distribution of COVID-19 is challenging healthcare systems worldwide. In many countries hospitals and ICU departments are overloaded or fear a potential collapse - the optimal allocation of healthcare resources is required. Healthcare professionals are forced to treat severely ill patients with limited access to ventilation equipment,...

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