• Medical Device & AI Regulations

    The quickly evolving major presence of Artificial Intelligence in healthcare means the current regulatory landscape is changing. AI-based medical devices are rapidly revolutionising the industry across the globe, but along with the many positive developments made in healthcare delivery, calls for more regulatory oversight are growing. Many countries...

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  • WHO Strengthens Medical Device Regulation as Machine Learning-Enabled Medical Devices Gather Pace

    Effective regulatory systems are an essential component of health system strengthening and contribute to better public health outcomes, even more so in the age of medical devices that are enabled by machine learning.   Key Points Without medical devices, many critical healthcare procedures would not be possible. WHO provides guidance...

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  • Effective Management in Times of Health Crisis

    The COVID-19 pandemic and the rapid evolution of events on a national and international scale required the adoption of immediate and effective measures to deal with these events .   Key Points The rapid responsiveness of Public Procurement Units to the pandemic. The need for public-private partnerships is illustrated. The importance...

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  • How Imaging Generative AI Will Transform the Medical Radiological Practice

    Generative AI imaging has emerged as a powerful tool in radiology, allowing for the creation of highly detailed bio-models that can assist in diagnosis and treatment planning. Generative AI algorithms can generate 3D models of organs, tissues, and other structures with unprecedented accuracy and speed. This technology thus has the potential...

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  • Organ Support

    When patients are critically ill, one or more organs may not function optimally or even fail, so organ support is an important component of ICU management.   However, organ support can be associated with complications such as infections, bleeding, and damage to surrounding tissue or organs. These complications can alter the patient's condition,...

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  • Combined Extracorporeal Lung and Kidney Support in Fluid Overload

    During artificial organ support, kidney injury is multifactorial and related to the high severity of patients treated with extracorporeal membrane oxygenation (ECMO). The successful delivery of continuous renal replacement therapy (CRRT) during ECMO requires a clear prescription of the target solute clearance and fluid removal rate based on the cumulative...

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  • Which Vasopressors and Inotropes to Use in the Intensive Care Unit

    Vasopressors and inotropes are frequently used in intensive care units. With a special focus on recent studies, this article summarises the key messages in the management of patients requiring inotropes and vasopressors.   Introduction Cardiac output (CO) is a key determinant of oxygen delivery. Low cardiac output syndrome (LCOS) causes...

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  • A Very Old Patient in the ICU: Much More Than an Acute Organ Dysfunction

    Treating an elderly patient in intensive therapy requires the integration of many components. The purpose of this paper is to promote a comprehensive assessment of the critically ill patient aged 80 or more years.   Introduction Ageing of the population combined with a shortage of intensive care unit (ICU) beds results in a demand for...

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  • Kidney Replacement Therapy in the Intensive Care Unit

    Kidney Replacement Therapy is a commonly used therapeutic strategy in the intensive care unit for patients who develop Acute Kidney Injury or who already have a diagnosis of chronic kidney disease. ICU staff should know when to use it and which type is most suitable for the circumstances.   Epidemiology and Outcomes of AKI Acute kidney...

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  • Predictive Analytics for Kidney Support in the ICU

    The timing and application of dialysis in the ICU is highly variable contributing to poor outcomes. A clinical decision support system (CDSS) incorporating a dynamic predictive algorithm for organ support could improve outcomes.   Background Multiorgan failure (MOF) and acute kidney injury (AKI) are frequently encountered in critically...

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