• Xenon limits brain damage following cardiac arrest

    Xenon and brain injury. Xenon, a chemically inert but biologically active monatomic gas, has been applied in patients for anaesthesia/sedation, and most recently in the critical care of patients with acute ongoing neurological damage. Following preclinical evidence that xenon has ameliorative activity in several pathobiologic...

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  • What’s new in sepsis in children?

    The latest in diagnosis and treatment. Sepsis is a life-threatening condition in children. Current paediatric definitions are based on systemic inflammatory response syndrome. Since the publication of the third international consensus definitions for sepsis and septic shock for adults, efforts in paediatrics are focused on finding a definition...

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  • Optimising sleep in the ICU

    Disordered sleep is common in ICU patients. While many of the reasons for this are impossible to modify, and others rely on improvement in the underlying condition, many directly depend on the actions of the treating team: for example, exposure to noise, timing of therapeutic procedures, tapering of sedating drug doses, and daytime mobilisation....

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  • What should we stop doing in the ICU?

    In this article, I highlight that the most important thing intensive care physicians should stop doing is ignoring that they are prone to several cognitive biases. I will first support my statement by looking for conceptual caveats and cognitive bias in routine intensive care unit (ICU) care, and then move to specific patient and structural problems....

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  • Caring for very old patients in the ICU

    Describes the epidemiology and outcomes for very old patients as known in 2018, along with a short introduction to the most relevant “geriatric syndromes” important also for intensivists, and discusses where we should increase our body of knowledge to make a more precise triage in this patient group. The very old ICU patient is a term often...

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  • Humanizing the ICU experience with enhanced communication

    Avicenne ICU’s initiative. Decisions to limit therapy (DTLT) are routine for ICU physicians. Although breaking bad news is one of the most difficult tasks clinicians face, ongoing communication is even more crucial as families (not necessary following a legal or genetic definition) of critically ill patients have heightened communication...

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  • Implementing ECCO2R and vv-ECMO in non-academic centres

    Shares experiences of implementing extracorporeal life support in a non-academic hospital. Acute respiratory distress syndrome (ARDS) is a life-threatening disorder characterised by severe impairment of gas exchange. The most common causes are pneumonia, sepsis and acute pancreatitis. It is accurately defined in the Berlin definitions...

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  • Improving access to safe anaesthesia

    Interview with Jannicke Mellin-Olsen, President, World Federation of Societies of Anaesthesiologists. Jannicke Mellin-Olsen, MD, DPH is Consultant Anaesthesiologist at the Department of Anaesthesia, Intensive Care and Emergency Medicine, Bærum Hospital, Norway. She is President of the World Federation of Societies of Anaesthesiologists, and...

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  • Highlights from the I-I-I Blog

    (I expert, I question, I answer)  Have you got something to say? Visit  https://healthmanagement.org/c/icu/list/blog  or contact [email protected] Jean Baptiste Lascarrou Medical Intensive Care Unit, Nantes University Hospital, France @jblascarrou Epinephrine for out-of-hospital cardiac arrest “Epinephrine...

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  • Key decisions in a goal-directed coagulation management approach

    An individualised goal-directed approach to managing coagulopathy is recommended to treat bleeding trauma patients. Severe trauma is a great burden to society, with millions of victims worldwide. If trauma patients are hazardly bleeding, surgical bleeding requires the surgeon to fix the problem, while coagulopathy requires management...

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