Search Tag: heparin

ICU Management

Heparin-induced-thrombocytopaenia

2023 20 Apr

Heparin-induced thrombocytopaenia (HIT) is an immune complication of heparin therapy. This review discusses the pathophysiology, incidence, clinical manifestations, diagnostic approach, and management of patients with HIT.   Pathophysiology HIT is an immune complication of heparin therapy caused by IgG antibodies to complexes of platelet...Read more

ICU Management

Isicem23-effects-of-therapeutic-dose-heparin-in-hospitalised-patients-with-covid-19

2023 21 Mar

At the #ISICEM23 this week in Brussels, the benefits and harms of therapeutic-dose heparin varied by hospitalised COVID-19 patient characteristics were discussed, and the importance of considering the heterogeneity of treatment effect (HTE) in the design and analysis of randomised clinical trials was highlighted.   To date, RCTs that have tested...Read more

ICU Management

Nebulised-heparin-for-patients-with-ards

2021 25 Jan

Mechanical ventilation in the ICU for 48 hours or longer is known to be associated with ARDS, which could be present either when ventilatory support is initiated or develop afterwards, typically during the first five days. ARDS affects approximately 23% of mechanically ventilated, critically ill patients and has a mortality of nearly 46%. Patients...Read more