Search Tag: drug toxicity

ICU Management

Pharmacokinetic-pharmacodynamic-principles-to-combat-antimicrobial-resistance

2022 14 Oct

Pharmacodynamic and pharmacokinetic principles play a central role in antimicrobial dose-optimisation to combat antimicrobial resistance. In the future, research focused on the integration of preclinical and clinical data is paramount. Antimicrobial Resistance in the ICU The use of antimicrobial drugs in the hospital is very common...Read more

ICU Management

Roche-receives-fda-clearance-for-the-cobas-cdiff-test-to-detect-clostridium-difficile

2015 04 Jun

Roche (SIX: RO, ROG; OTCQX: RHHBY) has announced that the US Food and Drug Administration (FDA) has provided 510(k) clearance for the cobas Cdiff Test to detect Clostridium difficile (C. difficile) in stool specimens. The cobas Cdiff Test targets the toxin B gene found in toxigenic C. difficile strains directly in specimens from symptomatic patients....Read more

Executive Health Management

Fasting-improves-efficacy-of-low-toxicity-cancer-drugs

2015 01 Apr

Breast, colorectal and lung cancers may respond to a less-toxic class of drugs as well as they do to chemotherapy when the drugs are used in combination with fasting. The results of two new studies in mice, conducted by a multinational collaboration of researchers, have been published in the March 30 issue of Oncotarget . Starving Cancer Cells...Read more

Pharmacy Management

New-screening-method-may-identify-drug-toxicity

2015 11 Feb

A group of researchers from Weill Cornell Medical College in New York City have devised a drug screen that capitalises on the tendency of toxic compounds to alter the properties of the lipid bilayer that encases cells. The method is to be presented at the 59th annual meeting of the Biophysical Society. As far as drug development is concerned,...Read more