Search Tag: Sepsis

ICU Management

Paradigm shift in sepsis prevention

2018 15 May

There is a paradigm shift happening for sepsis. "Sepsis is no longer solely conceptualised as problem of individual patients treated in emergency departments and intensive care units but also as one that is addressed as public health issue with population- and systems-based solutions," says a commentary in the journal Critical Care. Such a shift, the... Read more

ICU Management

HHFT pioneers use of diagnostic tools for earlier optimisation for sepsis patients

2018 08 May

… Antimicrobial Susceptibility Testing (AST) times reduced from days to hours….   Hampshire Hospitals NHS Foundation Trust (HHFT) is pioneering the use of the Accelerate PhenoTM system from Accelerate Diagnostics, Inc., (Accelerate Diagnostics) a leading in vitro diagnostics company, to speed up and improve the diagnostic outcome of antibiotic treatment.... Read more

ICU Management

SeptiCyte LAB: new test aims to make sepsis molecular

2018 01 May

Sepsis is a life-threatening condition and early detection is critical to ensure that the patient receives timely and appropriate treatment. For almost 25 years, clinicians have used the systemic inflammatory response syndrome (SIRS) criteria, a measure of the clinical expression of the host response to inflammation, as a marker of sepsis. A new approach... Read more

ICU Management

Hyperchloraemia in sepsis: saline vs. balanced crystalloids

2018 03 Apr

Chloride, as the major anion of the extracellular fluid, constitutes an important element in the homeostasis of the human organism. Hyperchloraemia, whether a result of the sepsis process or a consequence of its treatment with supraphysiologic chloride fluids, appears to have a negative impact on the clinical outcome of septic patients, according to... Read more

ICU Management

New method for rapid sepsis diagnosis

2018 20 Mar

Sepsis is a life-threatening condition and early diagnosis is crucial to ensure that treatment is not delayed. However, as current diagnostic methods are imprecise, the condition is misdiagnosed in 30 percent of patients. Now a microfluidic device developed by Massachusetts General Hospital (MGH) for measuring neutrophil motility shows promise in the... Read more

ICU Management

Volume 18 - Issue 1, 2018

2018 16 Mar

Change content default value Read more

ICU Management

Improving diagnostic stewardship by using new microbiological technologies

2018 16 Mar

Describes an episode of sepsis in a leukaemia patient, whose treatment was early guided by using rapid diagnostics technology to identify the cause of infection. A 4-year-old patient under treatment for acute lymphoblastic leukaemia, diagnosed 6 months before, was admitted to the emergency room (ER) at midnight (00h33) due to a fever episode of less... Read more

ICU Management

Immune dysfunction in sepsis

2018 16 Mar

An overview of the recent advances in the diagnosis and treatment of immune system dysfunction in sepsis.Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection (Singer et al. 2016). Sepsis-induced immune system dysfunction is an important sequelae of sepsis. The persistence of immune system dysfunction... Read more

ICU Management

Gut microbes protect against sepsis

2018 16 Mar

New research published in Cell Host & Microbe suggests that gut bacteria may help in the fight against sepsis. In the study, mice were given particular microbes, which increased blood levels of immunoglobulin A (IgA) antibodies, protecting the mice against polymicrobial sepsis.You might also like: Study: Microbiome Disruption May Have Key Role in ARDS,... Read more