Search Tag: Sepsis
Microbiome in Sepsis and COVID-19
2021 30 Sep
Bacteria play a fundamental role in human life. Given the many roles of gut microbiota in critical illness and other pathological conditions, it is important to target therapeutical interventions to restore, preserve and enrich its composition. Introduction Bacteria play, for better or worse, a fundamental role in human life. As... Read more
Trends in Sepsis-Related Mortality in the U.S.
2021 27 Jul
Sepsis is a life-threatening organ dysfunction. It is the leading cause of death in the U.S. It is also one of the most expensive conditions to treat. However, the burden of sepsis-related mortality in the U.S. in recent years is not well-characterised. Previous studies utilise hospital databases and electronic health records to determine trends, but... Read more
Association of Volume of Sepsis Cases and Mortality
2021 06 Jul
Sepsis is a leading cause of death worldwide and is also associated with a high burden of patient mortality. This burden is expected to increase as populations age. Patients with sepsis typically require high-cost interventions in ICUs. Even with urgent treatment, the probability of death still remains high. However, ICUs that have more experience... Read more
Algorithm that Predicts Deadly Hospital Infection Misses 67% of Cases
2021 28 Jun
A study published in JAMA Internal Medicine found that a system used to identify cases of sepsis missed most instances and frequently issued false alarms. Sepsis accounts for nearly 1 million hospitalisations in the US annually and is a major contributor to hospital length of stay, healthcare costs, and in-hospital mortality (up to 15%).... Read more
Culture-Negative and Culture-Positive Sepsis or Septic Shock
2021 19 May
Incidence of sepsis and septic shock has been increasing consistently, and the morbidity and mortality associated with this is an area of concern. Mortality from sepsis and septic shock is quite high, ranging between 20 to 40%. Guidelines for sepsis and septic shock recommend the application of broad-spectrum antibiotics. There is clinical evidence... Read more
Antibiotic Delay Intervals, Mortality Among Patients With Suspected Sepsis
2021 27 Apr
Timely delivery of antibiotics is a major cornerstone of sepsis therapy. Clinical evidence suggests that every one-hour delay in antibiotics after emergency department (ED) triage or the onset of organ dysfunction or shock could result in a 3-7% increase in the odds of a poor outcome. The Surviving Sepsis Campaign (SSC) guidelines recommend antibiotic... Read more
The Challenge of Admitting a Very Old Patient with Sepsis to an Intensive Care Unit
2021 19 Apr
Sepsis incidence in very old patients is high and related mortality and morbidity are a major health concern. Frailty and severity of illness, not just age or sepsis diagnosis, are the determinant factors in outcome. Early identification and treatment are decisive in their survival. N owadays, we are facing some important facts: there has... Read more
Biomarkers to Identify Acute Kidney Injury for Early Sepsis Detection
2021 23 Mar
Early recognition of sepsis is vital for improving patient outcomes. If detected on time, sepsis can be treated with antibiotics and source control, recognition and reversal of shock and organ support. The three most common organ dysfunctions in sepsis are cardiovascular, renal and respiratory. Cardiovascular and respiratory organ dysfunctions are... Read more
Resurgence of the BUN :Creatinine Ratio In Severe Illness: COVID-19, Sepsis, And Trauma
2021 31 Mar
Speakers John Toffaletti, Ph.D. Professor of Pathology, Director of ABG and CPED Labs Duke University Medical Center Dennis Begos, MD, FACS, FACRS Associate Medical Director, Medical and Scientific Affair Nova Biomedica l Find Nova Medical On Social Media Read more