Search Tag: Extracorporeal Membrane Oxygenation
2024 14 Oct
Extracorporeal membrane oxygenation (ECMO) is used to support critically ill patients, but its impact on antimicrobial pharmacokinetics (PK) and pharmacodynamics (PD) presents significant challenges. ECMO circuits can affect drug delivery, leading to the sequestration of drugs, changes in the volume of distribution (Vd), decreased clearance, and longer...Read more
2024 09 Sep
In patients with severe acute respiratory distress syndrome (ARDS), managing gas exchange and avoiding ventilation-induced lung injury (VILI) are key challenges. Venovenous extracorporeal membrane oxygenation (ECMO) is used for severe ARDS with persistent hypoxaemia, effectively improving gas exchange and reducing ventilation pressures, though...Read more
2024 09 Sep
Extracorporeal membrane oxygenation (ECMO) use is on the rise, but patients on ECMO often experience major complications, such as acute brain injury (ABI), which doubles or triples in-hospital mortality rates. ABI is more prevalent in venoarterial (VA) ECMO compared to venovenous (VV) ECMO, especially in cases involving extracorporeal cardiopulmonary...Read more
2023 06 Dec
The effectiveness of prone positioning to improve outcomes in patients with severe acute respiratory distress syndrome (ARDS) undergoing venovenous extracorporeal membrane oxygenation (VV-ECMO) compared to supine positioning is unknown. The PRONECMO multicenter randomised clinical trial aimed to address the lack of robust evidence regarding prone...Read more
2023 08 Nov
The use of extracorporeal membrane oxygenation (ECMO) has risen significantly as a rescue therapy for respiratory issues, including those caused by viral infections. Patients on ECMO frequently experience complications like thrombotic events and major bleeding, which are considered ECMO-related issues. However, infections are typically attributed to...Read more
2023 13 Oct
Xenios sponsored a lunch symposium at the 16th European Conference on Paediatric and Neonatal Ventilation (EPNV) in Montreux (CH) in May 2023. Matteo Di Nardo (Italy) introduced the audience to extracorporeal membrane oxygenation (ECMO) in neonates. Florian Kipfmüller (Germany) presented current knowledge and his experience with ECMO in neonates...Read more
2023 28 Jun
A recent review explored the extent and quality of literature investigating the influence of social determinants of health (SDoH) on extracorporeal membrane oxygenation (ECMO) utilisation and outcomes among children and adults. The researchers examined the relationship between factors like socioeconomic status, education, and access to healthcare with...Read more
2023 20 Apr
During artificial organ support, kidney injury is multifactorial and related to the high severity of patients treated with extracorporeal membrane oxygenation (ECMO). The successful delivery of continuous renal replacement therapy (CRRT) during ECMO requires a clear prescription of the target solute clearance and fluid removal rate based on the cumulative...Read more
2023 20 Apr
Extracorporeal membrane oxygenation is a resource that is accessible in hospitals and intensive care units all over the world. In serious situations, ECMO therapy is intended to provide haemodynamic and/or ventilatory support. Because of this, many people refer to the ECMO patient as "the most critical patient." As a result, there is a very high...Read more
2023 15 Feb
There is increasing evidence supporting the use of extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) in patients that do not respond to maximal medical therapy. ARDS can occur in some COVID-19 patients who are hospitalised, and ECMO can be utilised as a treatment option in some cases. Using ECMO can help...Read more
2022 23 Nov
Extracorporeal membrane oxygenation (ECMO) refers to mechanical support in patients for heart or lung function during cardiopulmonary failure. ECMO is used when conventional treatments have failed. As per the international guideline of the Extracorporeal Life Support Organization (ELSO), ECMO should be considered when the estimated mortality risk is...Read more
2021 01 Sep
At the 40th ISICEM International Symposium on Intensive Care & Emergency Medicine this week, Professor Alain Combes of Sorbonne University, Paris, talked about treating COVID-19 patients with the most severe forms of cardiac and respiratory failure. Prof Combes talked about his experience during the pandemic and presented his research that compared...Read more
2021 28 Jun
The use of venovenous extracorporeal membrane oxygenation (VV-ECMO) in patients with severe acute respiratory distress syndrome (ARDS) has increased substantially over the last few years. However, conclusive evidence supporting its use is still lacking, and mortality of patients treated with VV-ECMO for ARDS is still high. Optimal strategies of...Read more
2021 22 Jun
Extracorporeal membrane oxygenation (ECMO) has been used in patients with COVID-19 who develop severe acute respiratory distress syndrome (ARDS). ECMO has previously been used in other infectious outbreaks, including the 2009 influenza A (H1N1) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) outbreak. The Extracorporeal Life Support...Read more
2020 26 Feb
The US FDA (Food and Drug Administration) has granted 510(k) approval to Fresenius Medical Care North America and Xenios, a Fresenius Medical Care company, for long-term use of its Novalung system for patients with acute lung failure or acute cardiopulmonary failure. The FDA announced this on Friday evening. With class II approval, the Novalung...Read more
2019 30 Aug
Acute Respiratory Distress Syndrome (ARDS) affects up to 10% of patients in the ICU. Typical symptoms of ARDS include an increase in lung weight and a reduction of aerated lung tissue. For the treatment of ARDS alveolar recruitment is key, however, this has not yet been shown to benefit severe ARDS cases. It has been suggested that lung recruitment...Read more
2019 20 Feb
Despite limited evidence, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for the management of refractory cardiogenic shock (RCS) while awaiting myocardial recovery or the bridge to long-term assistance or transplantation. However, despite technological advances and better quality of care, mortality still remains at...Read more
2018 26 Sep
Over the past decade, extracorporeal membrane oxygenation (ECMO) has become mainstream therapy in adult intensive care. Although the list of contraindications to ECMO has shrunk considerably, a few of these remain absolute, notes Dr. Graeme MacLaren in an editorial article published in the journal Critical Care. "There are a number of circumstances...Read more
2018 11 Jul
An analysis of ECMO – extracorporeal membrane oxygenation – use in patients with cardiogenic shock finds that mortality remains high despite increasing utilisation of the resource-intensive intervention in this population. Season of admission (other than Fall) and presence of specific comorbidities (respiratory and genitourinary diseases) are associated...Read more
2017 19 Dec
Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy in acute respiratory distress syndrome (ARDS) patients but is associated with complications and costs. Researchers in Germany have developed a new, simple model that also incorporates extrapulmonary variables to predict mortality in ECMO-treated ARDS patients. The PRESET-Score (PREdiction...Read more
2017 04 Jul
Extracorporeal membrane oxygenation (ECMO) can support severe derangements in gas exchange in both acute and chronic respiratory failure, with data showing potential for improving survival in patients with high rates of morbidity and mortality, according to a review paper to appear in the journal CHEST. The use of ECMO for respiratory failure in adults...Read more
2016 07 Jul
While the role of extracorporeal membrane oxygenation (ECMO) for in-hospital cardiac arrest has good evidence, the benefit of using it for out-of-hospital cardiac arrest (OHCA) is less clear. Favrizio Cirillo, Department for Anaesthesiology and Intensive Care Medicine, University Hospital Cologne, Germany, and colleagues have recently published a...Read more
2016 11 Mar
Improved Outcomes of Immunocompromised Patients Admitted to the ICU Immunocompromised patients, who include patients with haematological malignancies (HMs), solid tumours, solid-organ transplants, human immunodeficiency virus (HIV) or long-term corticosteroid use, are increasingly admitted to intensive care units (ICUs). Their survival has improved...Read more
2016 11 Mar
The rationale, indications and challenges of extracorporeal lung assist in trauma patients with severe acute respiratory distress syndrome is given on the basis of clinical and scientific experience. Traumatic lung injury is often present in multiple trauma with a wide spectrum of severity. In a large cohort study, patients with multiple trauma...Read more
2016 11 Mar
Since its first clinical use in the 1950s, the set-up and management of the heart-lung machine (HLM) has been the responsibility of the perfusionist, who has a documented competency in every facet of extracorporeal technology because of their theoretical and practical training. In contrast, when this technology leaves the operating room to provide...Read more
2016 11 Mar
In-Line Bedside Blood Gas Analysis Enables Rapid Results For Respiratory Support Management Extracorporeal membrane oxygenation (ECMO) is an acute support system used to aid heart and lung function in patients with severe respiratory or cardiac failure. Having its origins in the operating theatre, the use of ECMO has now migrated into the ICU....Read more