High quality nucleic acids are a key for downstream applications like genotyping, sequencing and real-time PCR analysis. Together with MACHEREY-NAGEL, we have designed the Genomic STARlet that can run up to eight methods on one instrument to reach minimal variation and optimal standardization. Nucleic acid extraction, isolation and purification from biological samples and PCR products in a non IVD environment. The Genomic STARlet is an all-rounder: it can handle different input samples such as blood, tissue and cells. More than half a dozen nucleic acid extraction kits have been tested on the system. Standard sample input and output labware from MACHEREY-NAGEL is already predefined. It can be selected when a run is started. The processes are optimized to save time and minimize tip consumption. Depending on the kit, 96 samples can be processed in 60-144 minutes. Several runs can be performed every day.