The Cryo-S Mini device is suitable for immediate, local and efficient freezing of tissues through the use of wide range of contact cryoapplicators and spraying cryoapplicators that allows freezing of minute (cubic millimeters) and large (cubic centimeters) lesions. This is done by directly spraying liquid nitrous oxide to the treated lesionThe Cryo-S Mini can be used for minor surgeries and does not require an electric power supply.