The Esco Airstream Class III biohazard safety cabinets are high quality products with an angles front. Minimal contamination is guaranteed because of the patented Esco ISOCIDE antimicrobial surface on all painted surfaces. Issues regarding migration of the pathogenic materials are minimized because the cabinet operates at negative pressure relative to the laboratory. Audible and visible alarms for airflow are provided are provided through the microprocessor-based Esco Sentinel™ Silver control. Compared to the single-stage designs the Esco Airstream Class III biohazard safety cabinets provide >100,000 times better protection because the presence of exclusive dual exhaust filters. The high-quality ULPA filters (per IEST-RP-CC-001.3) filters the exhaust air twice; >99.999% for 0.1 to 0.3 micron particles, better than HEPA filters. The operator can monitor the work area pressure using the magnehelic* pressure gauge. Maximum protection is guaranteed with Neoprene™ gauntlets; integrated pass-through with interlocking doors.