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Intensivist Department of Critical Care Medicine Ghent University Hospital
Associate Professor Ghent University Ghent, Belgium
ICU Management & Practice Editorial Board Member
Ongoing research and challenges regarding the use of Artificial Intelligence and Machine Learning to leverage data and identify complex interactions to address antimicrobial resistance in the ICU. The possibilities of artificial intelligence (AI), and more specifically, machine learning (ML), are being researched across almost all domains of medicine, and the field of intensive care
READ MOREPharmacodynamic and pharmacokinetic principles play a central role in antimicrobial dose-optimisation to combat antimicrobial resistance. In the future, research focused on the integration of preclinical and clinical data is paramount. Antimicrobial Resistance in the ICU The use of antimicrobial drugs in the hospital is very common with approximately 35% of the patients on an adult...
READ MOREIn the past decades there have been significant advances in the diagnosis and management of patients with sepsis and septic shock, and overall awareness has increased significantly (Angus and van der Poll 2013). Emphasis is currently on the early detection of sepsis and rapid initiation of fluid administration and antibiotic therapy, all of which have improved outcomes (Rhodes et al. 2017)....
READ MOREMultidrug resistance (MDR) is increasing worldwide and has been acknowledged as one of the major threats to healthcare by the World Economic Forum and the World Health Organization (World Health Organization 2014). Intensive care unit (ICU) patients seem to be particularly susceptible for acquiring MDR organisms, either just as colonisers, or as pathogens causing invasive infection. This increased
READ MORERecently a number of new antibiotics or combinations for complicated intra-abdominal infections have been introduced. Here we review the currently available data of these new drugs and discuss how they can be used in critically ill patients with complicated intraabdominal infections. Complicated intra-abdominal infections (cIAI) remain one of the most challenging infections in the intens
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Professor Jan De Waele is an intensivist at the Surgical ICU of the Ghent University Hospital in Ghent, Belgium. As the current President of WSACS – the Abdominal Compartment Society, he will host...
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