A majority of stroke patients have problems paying attention and
could be helped by brain-training computer games, a new study suggests.
Researchers at Imperial College London found that problems such as
difficulty filtering out distractions, difficulty following
instructions, and reduced alertness are much more common in stroke
patients than doctors realise.
Their study, published in Neurology, showed that brain scans and bedside tests can be used to diagnose these three types of attention problems, each of which could be addressed with computer games tailored for the patient’s requirements.
An estimated 150,000 people in the UK have a stroke each year. It can
cause a wide range of effects on the mind and body, including problems
with memory, attention and speech; emotional problems and physical
The study involved 110 patients being treated at Charing Cross
Hospital, a major centre for stroke care in west London. Five of them
were already diagnosed with a serious attention disorder called neglect,
but computerised tests showed that over half of them had attention
problems that hadn’t been recognised.
The type of problem appeared to depend on which part of the brain had
been affected by the stroke. Patients with strokes affecting the front
of the brain had difficulty filtering out distraction; strokes towards
the back of the brain caused difficulty following instructions; while
strokes in the centre of the brain caused a general reduction in
The researchers suggest that doctors could use brain scans to predict
what type of problem a stroke patient would be likely to have.
Computerised tests could then confirm the diagnosis, and the patient
could be offered therapy based on their individual condition.
The study’s senior author, Dr Paul Bentley, from the Department of
Medicine at Imperial College London, said: “We found that more than half
of stroke patients have some form of attention problem, and these may
be missed by routine bedside examinations.
“We’ve shown that specialised computer games are very sensitive at picking up deficits in stroke patients. They can also be tailor-made for each patient to rehabilitate them for the specific deficit they show. These findings therefore suggest a new strategy by which stroke treatments can be personalised depending on information gained from patients’ brain scans.”
Patients might also benefit from tailored drug therapies, Dr Bentley
said. The three types of attention problems the researchers found
correspond to three networks in the brain controlled by different brain
chemicals. Drugs that modulate the release of these chemicals are
already available for use in other neurological conditions, which the
researchers suggest exploring as specific treatments for patients with
different types of impairments.
The study was funded by the National Institute for Health Research Imperial Biomedical Research Centre.