Traumatic Brain Injury Associated with Premature Death
The team of researchers studied all patients born in 1954 or later in Sweden who were diagnosed with TBI from 1969 to 2009, amounting to a total of over 200,000 people.
Among 11,053 patients with premature death after TBI, 2,378 (21.5%) died six months or later after diagnosis. The authors compared mortality rates six months or more after TBI with controls (n=2,163,190) and unaffected siblings of patients with TBI (n=150,513).
Compared to patients without TBI, those who had survived six months following TBI displayed a higher risk of dying, with the risk remaining for years after the TBI.
Death from external causes, including suicide, injury and assault, also was a higher risk and if they had psychiatric or substance abuse conditions, patients with TBI also were at risk for premature death with 61% of premature deaths in TBI patients with a psychiatric or substance abuse diagnosis.
The authors concluded that current clinical guidelines may need revision to reduce mortality risks beyond the first few months after injury, and address high rates of psychiatric comorbidity and substance abuse.
16 January 2014
Published on : Fri, 17 Jan 2014
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