Search Tag: septic shock
2018 16 Oct
In the past decades there have been significant advances in the diagnosis and management of patients with sepsis and septic shock, and overall awareness has increased significantly (Angus and van der Poll 2013). Emphasis is currently on the early detection of sepsis and rapid initiation of fluid administration and antibiotic therapy, all of which...Read more
2018 16 Oct
The latest in diagnosis and treatment. Sepsis is a life-threatening condition in children. Current paediatric definitions are based on systemic inflammatory response syndrome. Since the publication of the third international consensus definitions for sepsis and septic shock for adults, efforts in paediatrics are focused on finding a definition...Read more
2018 13 Sep
A state-wide mandated public reporting of compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. In "Mortality Changes Associated with Mandated Public...Read more
2017 22 Aug
In a new analysis, 57% of patients meeting old definition for septic shock did not meet Sepsis-3 criteria. Although Sepsis-3 criteria identified a group of patients with increased organ failure and higher mortality, those patients who met the old criteria and not Sepsis-3 criteria still demonstrated significant organ failure and 14% mortality rate....Read more
2017 13 Jun
According to a new study, the use of a multifaceted intervention including an electronic sepsis alert (e-alert) system with sepsis response team was associated with improvement in care processes of sepsis and septic shock and patient outcomes. The findings are reported in the journal Annals of Intensive Care. Although sepsis is a leading cause of...Read more
2017 22 May
Prompt antibiotic initiation is associated with improved mortality in sepsis and septic shock. However, new research shows that patients with sepsis, a life-threatening complication of an infection, had delays approaching one hour in being given antibiotics when seen in emergency rooms that were overcrowded. The findings were presented at the 2017...Read more
2017 17 Apr
A new study reported in the journal CHEST demonstrates the beneficial effects of high-dose intravenous vitamin C in reducing mortality in patients with severe sepsis. However, an Editorial published in the same issue of CHEST, calls for more studies to determine optimal dose of vitamin C in the critically ill population. See Also : Albumin Administration...Read more
2017 21 Mar
Patients with septic shock admitted to hospitals affected by the 2011 shortage of the drug norepinephrine had a higher risk of in-hospital death, according to a study presented at the 37th International Symposium on Intensive Care and Emergency Medicine. See Also : New Strategy for Identifying Sepsis Arising in the ICU The study, also published...Read more
2017 01 Mar
An Editorial in the journal Chest emphasises the need to develop highly accurate, flexible methods for identifying patients with septic shock to ensure these patients are appropriately treated and hospitals are reliably assessed for treating these patients. Sepsis is now the most costly hospital condition and the most common diagnosis among patients...Read more
2017 24 Jan
The Surviving Sepsis Campaign , an initiative of the Society of Critical Care Medicine, the European Society of Intensive Care Medicine and the International Sepsis Forum, has released the 2016 Surviving Sepsis Campaign (SSC) guidelines for the management of severe sepsis and septic shock. The document, published simultaneously in Critical Care Medicine...Read more
2016 03 Oct
The results of the first randomised controlled trial investigating the effects of adjunctive early low-dose hydrocortisone to prevent progression to shock in patients with severe sepsis presenting without shock are published in JAMA today. There were no significant differences between treatment groups with regard to mortality or length of stay in...Read more
2016 27 Sep
A multicentre trial investigating early use of vasopressin compared to norepinephrine to treat septic shock found no reduction in the number of kidney failure-free days. The results of the VAsopressin vs. Noradrenaline as Initial therapy in Septic sHock (VANISH) trial are published in JAMA (Gordon et al. 2016). Patients who had septic...Read more
2016 09 Aug
A study was conducted to determine whether high dose intravenous sodium selenite treatment and procalcitonin-guided anti-infectious therapy in patients with severe sepsis affect mortality. The findings are published in JAMA Internal Medicine . Patients with severe sepsis suffer from oxidative stress that could contribute to multiorgan failure and...Read more
2015 04 Jan
A new study, published in BMC Medical Informatics and Decision Making, aimed to determine the diagnostic accuracy of an electronic alert system in detecting severe sepsis or septic shock in ED patients. The study was carried out at a tertiary academic medical centre in Saudi Arabia. The results showed high specificity and sensitivity and negative...Read more
2014 06 Nov
Most patients now survive a hospital stay for septic shock, although 23 percent of these patients will return to the hospital within 30 days, according to a new study. The number is noticeably higher than the normal readmission rate at a large academic medical centre, researchers reported. The study findings have been published in Critical Care Medicine...Read more
2014 18 Mar
According to an Australian/New Zealand study, released early in JAMA to coincide with its presentation at the International Symposium on Intensive Care and Emergency Medicine, it appears that during the years 2000 to 2012, a reduction in the risk of death for critically ill patients suffering from severe sepsis or septic shock was registered. This...Read more
2013 18 Sep
Cells called macrophages explode when bacteria enter them and trigger an immune response through a sequence of events that UNC researchers uncovered. Credit: Jon Hagar and Ine Jørgensen. The body’s immune system is set up much like a home security system; it has sensors on the outside of cells that act like motion detectors — floodlights —...Read more