Search Tag: immunosuppression

ICU Management

Immunotherapy effects on sepsis

2019 01 May

A randomised controlled multicentre trial assessed for the first time the safety and pharmacokinetics of an antiprogrammed cell death-ligand 1 (anti–PD-L1) immune checkpoint inhibitor (BMS-936559; Bristol-Myers Squibb, Princeton, NJ) and its effect on immune biomarkers in participants with sepsis-associated immunosuppression. Results show that... Read more

ICU Management

Cancer patients in the intensive care unit

2018 16 Oct

Recent advances and new challenges. It has been thought for years that cancer patients have not benefitted from intensive care unit (ICU) admission when they suffer from severe and potentially reversible acute illnesses. Fortunately, numerous studies have shown that this is not the case. Today, the number of cancer patients in ICUs around the... Read more

ICU Management

How Circadian Disruption Affects ICU Patients

2016 20 Dec

While circadian dysrhythmias in ICUs exist — expressed mainly as sleep deprivation, delirium incidence, and immunosuppression — hospitals have not taken adequate measures to overcome factors that lead to sleep disturbance, according to a review to appear in Journal of Critical Care. The manuscript is already available online, following acceptance for... Read more