Search Tag: hypoxia

ICU Management

COV-AID Trial: Effect of Anti-Interleukin Drugs in COVID-19

2021 02 Nov

The coronavirus infection continues to cause significant morbidity and mortality. COVID-19 is a new illness, and clinicians are still trying to find the most effective treatment strategies. Interleukin (IL)-1 and IL-6 blockade have been proposed as one possible option. However, study results so far are conflicting.   COV-AID, a prospective, multicentre,... Read more

ICU Management

Intubation Timing and COVID-19 ARDS Outcomes

2021 29 Jun

COVID-19 associated ARDS is associated with high mortality risk. Many patients with COVID-19 have been admitted with pneumonia and arterial hypoxaemia, increased work of breathing or impending fatigue. It is a common clinical practice to intubate patients with severe hypoxaemia. However, during the pandemic, there was a high demand for ICU beds. Therefore,... Read more

ICU Management

RECOVERY Trial: Tocilizumab in Hospitalised COVID-19 Patients

2021 16 Feb

A large majority of COVID-19 infections are mild or asymptomatic. However, there is a significant portion of individuals who develop severe respiratory illness that requires hospital care, and that could progress to critical illness with hypoxic respiratory failure requiring prolonged ventilatory support. This hypoxic respiratory failure is associated... Read more

ICU Management

Pulmonary Pathobiology of COVID-19

2020 27 May

The primary cause of death with COVID-19 is progressive respiratory failure. However, despite the widespread infection rates associated with COVID, very little is known about the pathophysiology of the disease. What clinicians do know is that the pathological features resemble acute respiratory distress syndrome (ARDS) and progressive hypoxia. But... Read more

ICU Management

Oxygen Therapy in Acute Care Medicine

2020 02 Feb

Oxygen therapy is a commonly used strategy in modern medicine. In most situations with declining oxygen saturations, clinicians are quick to use this technique. While effective in the setting of hypoxia, there are, however, some circumstances in which excess oxygen is indiscriminately administered for extended periods.  In healthcare, there has... Read more

Cardiology Management

New noninvasive method for detecting hypoxia

2017 12 Dec

Researchers at University of Illinois have developed a new, less invasive method for detecting hypoxia in tissue. The technique consists of a photoacoustic molecular probe that activates in tissues low in oxygen, which could lead to better diagnosis and treatment of cancer, stroke and blocked or narrowed blood vessels. In a paper published in Nature... Read more

ICU Management

Sherpas Have Superhuman Energy Efficiency

2017 29 May

New research suggests that Sherpas are superhuman mountain climbers and are extremely efficient at producing energy to power their bodies even when oxygen is scarce. Findings are published in the Proceedings of the National Academy of Sciences (PNAS). These findings could enable scientists to develop new ways to treat hypoxia in patients. A large... Read more

ICU Management

Volume 17 - Issue 2, 2017

2017 28 May

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ICU Management

High Altitude Research and its Relevance to Critical Illness

2017 28 May

Critical illness can be considered as the body’s failure to compensate for severe pathophysiological ‘stress’. The result is a vicious circle of damage that ultimately ends in organ failure, permanent harm and, unfortunately for many, death. Fortunately, the human body is remarkably resilient. It has the ability to tolerate changes to its internal... Read more

ICU Management

Teleflex Incorporated Announces Worldwide Voluntary Recall of Hudson RCI® LIFESAVER®

2015 29 Jun

Teleflex Incorporated announced today that the U.S. Food and Drug Administration (FDA) has classified the voluntary medical device recall of Hudson RCI® LIFESAVER® Neonate Manual Resuscitator as a Class 1 recall. FDA defines Class I recalls as, “a situation in which there is a reasonable probability that the use of or exposure to a violative product... Read more