Search Tag: hypoxia
Intubation Timing and COVID-19 ARDS Outcomes
2021 29 Jun
COVID-19 associated ARDS is associated with high mortality risk. Many patients with COVID-19 have been admitted with pneumonia and arterial hypoxaemia, increased work of breathing or impending fatigue. It is a common clinical practice to intubate patients with severe hypoxaemia. However, during the pandemic, there was a high demand for ICU beds. Therefore,... Read more
RECOVERY Trial: Tocilizumab in Hospitalised COVID-19 Patients
2021 16 Feb
A large majority of COVID-19 infections are mild or asymptomatic. However, there is a significant portion of individuals who develop severe respiratory illness that requires hospital care, and that could progress to critical illness with hypoxic respiratory failure requiring prolonged ventilatory support. This hypoxic respiratory failure is associated... Read more
Pulmonary Pathobiology of COVID-19
2020 27 May
The primary cause of death with COVID-19 is progressive respiratory failure. However, despite the widespread infection rates associated with COVID, very little is known about the pathophysiology of the disease. What clinicians do know is that the pathological features resemble acute respiratory distress syndrome (ARDS) and progressive hypoxia. But... Read more
Oxygen Therapy in Acute Care Medicine
2020 02 Feb
Oxygen therapy is a commonly used strategy in modern medicine. In most situations with declining oxygen saturations, clinicians are quick to use this technique. While effective in the setting of hypoxia, there are, however, some circumstances in which excess oxygen is indiscriminately administered for extended periods. In healthcare, there has... Read more
New noninvasive method for detecting hypoxia
2017 12 Dec
Researchers at University of Illinois have developed a new, less invasive method for detecting hypoxia in tissue. The technique consists of a photoacoustic molecular probe that activates in tissues low in oxygen, which could lead to better diagnosis and treatment of cancer, stroke and blocked or narrowed blood vessels. In a paper published in Nature... Read more
Sherpas Have Superhuman Energy Efficiency
2017 29 May
New research suggests that Sherpas are superhuman mountain climbers and are extremely efficient at producing energy to power their bodies even when oxygen is scarce. Findings are published in the Proceedings of the National Academy of Sciences (PNAS). These findings could enable scientists to develop new ways to treat hypoxia in patients. A large... Read more
High Altitude Research and its Relevance to Critical Illness
2017 28 May
Critical illness can be considered as the body’s failure to compensate for severe pathophysiological ‘stress’. The result is a vicious circle of damage that ultimately ends in organ failure, permanent harm and, unfortunately for many, death. Fortunately, the human body is remarkably resilient. It has the ability to tolerate changes to its internal... Read more
Teleflex Incorporated Announces Worldwide Voluntary Recall of Hudson RCI® LIFESAVER®
2015 29 Jun
Teleflex Incorporated announced today that the U.S. Food and Drug Administration (FDA) has classified the voluntary medical device recall of Hudson RCI® LIFESAVER® Neonate Manual Resuscitator as a Class 1 recall. FDA defines Class I recalls as, “a situation in which there is a reasonable probability that the use of or exposure to a violative product... Read more
Study: Hypoxia, Hypotension 'Deadly Combo' in TBI
2014 21 Nov
Prehospital hypoxia and hypotension have been known to increase mortality in the setting of traumatic brain injury (TBI). Results of a new study showed that while hypoxia and hypotension increased mortality by four- and threefold respectively, the combination of these two factors further increased mortality by 14-fold. The largest previous study had... Read more