Search Tag: heterogeneity of treatment effect

2025 12 Mar

Community-acquired pneumonia (CAP) is a leading cause of hospitalisation with high mortality. It can be caused by various pathogens, including viruses, bacteria, and fungi, complicating treatment. Adjuvant corticosteroid treatment may help reduce excessive inflammation, which is linked to higher mortality.    While RCTs and a meta-analysis suggest...Read more

2023 21 Mar

At the #ISICEM23 this week in Brussels, the benefits and harms of therapeutic-dose heparin varied by hospitalised COVID-19 patient characteristics were discussed, and the importance of considering the heterogeneity of treatment effect (HTE) in the design and analysis of randomised clinical trials was highlighted.   To date, RCTs that have tested...Read more