Search Tag: fluid resuscitation
2025 04 Sep
Sepsis is a life-threatening, dysregulated immune response often leading to hypotension and multisystem organ dysfunction, with acute kidney injury (AKI) being the most common organ failure in critically ill patients. Traditional broad therapies for sepsis have largely failed due to the heterogeneity of the syndrome. Recent approaches focus on identifying...Read more
2025 22 Apr
Non-burn dermatologic emergencies, although less common than burn injuries, are associated with high morbidity and mortality due to the extensive loss of the skin barrier. These conditions often mimic burn-related pathophysiology and demand urgent, multidisciplinary care. Optimal outcomes are typically achieved at specialised burn centres, but limited...Read more
2022 29 Aug
Peripheral tissue hypoperfusion is a strong predictor of poor outcomes in patients suffering from severe conditions, such as sepsis, cardiac arrest or cardiogenic shock. The evaluation of peripheral tissue perfusion is very important in identifying shock patients. This can be done at the bedside with either semi-quantitative tools such as the mottling...Read more
2020 03 Feb
Initial fluid resuscitation practices for patients with haemodynamic shock remain controversial. There is significant variability in these practices, and the impact of this is still poorly understood. Overall, non-patient-centred resuscitation practices, conflicting treatments, variability, and failure to meet targets for initial resuscitation are...Read more
2019 23 Apr
Sepsis remains the most common cause of vasodilatory shock worldwide. The mainstay of haemodynamic treatment of septic shock is fluid resuscitation followed by vasopressors where fluids alone are insufficient to achieve target blood pressure. This article, published in the journal Critical Care, proposes the concept of “broad spectrum vasopressors”...Read more
2018 18 Dec
Researchers performed a systematic review and meta-analysis to evaluate data from randomised controlled trials (RCTs) of crystalloids and colloids for fluid resuscitation in critically ill adults. They found that crystalloids were less effective than colloids at stabilising haemodynamic resuscitation endpoints such as adequate central venous pressure...Read more