Search Tag: clinical trials
The ICU of the Future (Including AI and Robotization)
2022 11 Dec
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COVID-19: Readjusting Clinical Trials
2020 02 Sep
Scientific research has been significantly disrupted because of COVID-19. The ability to conduct clinical trials in a safe and effective manner has been affected. Thousands of clinical trials have been suspended or stopped due to lockdown and other restrictions. There has also been a reorientation in clinical trial research towards COVID-19. ... Read more
The Landscape of COVID-19 Clinical Trials
2020 18 Jul
Introduction In an effort to gather evidence through scientifically rigorous trials to guide optimal management of COVID-19, researchers in the US have started multiple parallel clinical trials. In this systematic review, the researchers evaluate the characteristics and issues surrounding simultaneous trials being conducted. Methods This... Read more
Clinical Trials of Artificial Intelligence
2020 26 Feb
With the introduction of computers and advanced technology, the majority of patient data is now captured digitally. And this has allowed opportunities for machine learning. Today, machine learning is frequently used to make diagnosis or predict disease outcomes, optimise treatment decisions and determine the prognosis of patients. While there... Read more
4 Clinical Trials/Studies to be Presented at ISICEM 2017
2017 13 Mar
The results of some highly anticipated clinical trials and studies will be presented on 21 March 2017 at the opening ceremony of the 37th ISICEM in Brussels. The opening session will take place from 08.30-10.00 and will surely present some fascinating interpretations and conclusions, so mark your calendar to ensure you don’t miss it. The following... Read more
Open Clinical Trials: Are We Nearly There Yet?
2016 23 Jun
Laser imaging of sites in Cambodia has revealed details of ancient cities unknown till now to archaeologists . Will it take as long to reveal clinical trials data? OpenTrials is described as an “open free database and web service to identify, aggregate, store, match, index and share all available documents and data on all clinical trials.” It is... Read more
Sepsis Clinical Trials - Can Do Better?
2016 05 Apr
Mortality from sepsis remains high, and results of clinical trials have been disappointing. Changing trials design has the potential to improve treatment, according to leading experts in sepsis and acute heart failure. The results of their discussions, which were facilitated by the European Drug Development , are published in the Journal of Intensive... Read more
CHEST Trial - BMJ Stirs Controversy Over Data Release
2016 03 Mar
Use of starch for fluid resuscitation was suspended by European and U.S. regulators following publication in the New England Journal of Medicine of the results of the CHEST trial (Myburgh et al. 2012 ), which raised safety concerns. Fresenius Kabi, which makes hydroxyethyl starch (HES) products and was a sponsor of the CHEST trial, has claimed... Read more
Promising New Sepsis Treatment on the Horizon
2015 23 Nov
A promising new drug for sepsis will have its first clinical trials thanks to a new grant from the British Heart Foundation . The new drug, called L-257, has been shown to improve survival and reduce organ failure during sepsis in animal models. The BHF Translational Award was granted to Dr. James Leiper and his clinical collaborator Dr. Simon Lambden... Read more
Adaptive Clinical Trials - the Ethical View
2015 12 May
Adaptive clinical trials (ACTs) represent an innovative approach to trial design and conduct, where the primary goal of adaptations is to improve scientific value and statistical efficiency. In addition to having distinguishing scientific features, ACTs also may involve ethical considerations that differ from more traditional randomised controlled trials... Read more