Search Tag: bleeding

ICU Management

European-guidelines-management-of-bleeding-coagulopathy-following-trauma

2023 07 Mar

According to the Global Burden of Diseases, Injuries, and Risk Factors Study, trauma accounted for 8% of total deaths annually. Among adolescents aged 10-24 years, road injuries, self-harm, and interpersonal violence are the top causes of disability-adjusted life-years, and road injuries are ranked first in the 25-49 year age group. Post-traumatic...Read more

ICU Management

Treatment-options-for-factor-xa-inhibitor-related-bleeding

2019 26 Sep

Specific treatment options for factor Xa inhibitor-related bleeding, focusing on drugs like rivaroxaban, apixaban, and edoxaban.   Non-vitamin K oral anticoagulants (NOACs/DOACs) are direct reversible inhibitors of factor Xa. These drugs are also reversible inhibitors versus warfarin or other vitamin K antagonist that are used in Europe. Anticoagulants...Read more

ICU Management

European-guideline-on-managing-post-traumatic-bleeding-5th-edition

2019 02 Apr

An updated guideline on the management of significant bleeding and coagulopathy following major trauma has been released by the pan-European, multidisciplinary Task Force for Advanced Bleeding Care in Trauma. The document, published in the journal Critical Care, includes recommendations intended to guide the management of patients during the early...Read more

Cardiology Management

Use-of-aspirin-in-individuals-without-cardiovascular-disease

2019 24 Jan

Cardiovascular disease continues to be a leading killer in the US as well as around the globe. While the number of deaths from cardiovascular disease has reduced over the years, deaths from stroke and myocardial infarction have plateaued in the US. Since the prevalence of cardiovascular disease continues to be both a health and economic burden,...Read more

ICU Management

Is-pre-hospital-coagulation-management-in-trauma-feasible

2018 01 Jun

Coagulation management remains a formidable challenge in severely bleeding trauma patients. A strong rationale suggests starting treatment of trauma-induced coagulopathy in the pre-hospital phase. The burden of trauma is increasing worldwide, particularly in less well-resourced nations. There are an estimated 5 million deaths per year, more...Read more

ICU Management

Are-newer-anticoagulants-safer-than-warfarin

2018 03 Apr

A new study compared outcomes among patients with atrial fibrillation hospitalised for bleeding after starting anticoagulation (warfarin, dabigatran, or rivaroxaban). Results show rivaroxaban and dabigatran were associated with shorter hospitalisations; however, there were no differences in 30- and 90-day mortality. These findings suggest bleeding...Read more

IT Management

Improving-treatment-of-life-threatening-bleeding

2015 17 May

U.S. researchers have successfully field tested a system that analysed patient vital signs during emergency transport, finding that it could detect those with life-threatening bleeding before they arrive at the hospital, potentially saving lives. The study, published in the journal Shock , was conducted by researchers from Massachusetts General Hospital...Read more

Cardiology Management

Heart-catheterisation-arm-is-safer-access-point

2015 20 Mar

A new study shows that patients with acute coronary syndrome undergoing coronary angiogram, a procedure used to assess blockages in the heart's arteries, had a significantly lower risk of major bleeding and death if their interventional cardiologist accessed the heart through an artery in the arm rather than the groin. Researchers said the results,...Read more

Cardiology Management

Anticoagulant-bivalirudin-may-improve-outcomes-compared-to-heparin

2015 17 Mar

According to a study published in JAMA, patients who experienced a heart attack and underwent a percutaneous coronary intervention (PCI) show a decrease in adverse clinical events when they were given anticoagulant bivalirudin following the procedure.  Compared to heparin alone or heparin plus tirofiban, bivalirudin resulted in a reduction in adverse...Read more

Cardiology Management

Findings-enable-better-management-of-anticoagulant-related-bleeding

2015 26 Feb

According to a study published in JAMA, patients with oral anticoagulation-associated intracerebral haemorrhage, reversal of international normalised ratio (INR) below a certain level within 4 hours and systolic blood pressure less than 160 mm Hg at 4 hours were associated with lower rates of haematoma enlargement, and resumption of anticoagulant therapy...Read more

Cardiology Management

Nsaids-with-anti-clotting-medications-increased-risk-of-bleeding-cardiovascular-events

2015 25 Feb

A new study published in JAMA reveals that the use of non-steroidal anti-inflammatory drugs (NSAIDs) in patients on antithrombotic therapy after a heart attack is associated with an increased risk of bleeding and cardiovascular events such as a heart attack, stroke or cardiovascular death, even after short-term treatment.   Current guidelines recommend...Read more

Pharmacy Management

Inappropriate-aspirin-use-in-1-in-10-low-risk-heart-patients

2015 14 Jan

According to a new study published in the Journal of the American College of Cardiology , over 10 percent of patients in a representative sample of US cardiology clinics were inappropriately taking aspirin for the primary prevention of CVD. The study also found that the inappropriate use of aspirin in different cardiology practices varied from 0 to...Read more

Pharmacy Management

Aop-orphan-brings-thromboreductin-r-to-the-russian-market

2014 25 Nov

AOP Orphan, a European pioneer in the field of rare diseases, is expanding its sales area for the preparation of Thromboreductin® to include the Russian market. The drug is an innovative treatment option for patients afflicted by Essential Thrombocythemia (ET), a rare but serious bone marrow disease. The drug is currently available in core...Read more

ICU Management

Aabb-guideline-for-platelet-transfusions

2014 20 Nov

The AABB, formerly the American Association of Blood Banks, has developed a guideline on appropriate use of platelet transfusion in adult patients. The new guideline published in the Annals of Internal Medicine emphasises judicious use of the procedure to reduce patient risk and conserve resources. The guideline was developed following a systematic...Read more

Cardiology Management

High-risk-of-bleeding-with-dabigatran-in-afib

2014 05 Nov

According to a new study published in JAMA Internal Medicine , patients with atrial fibrillation who take the blood thinner dabigatran are at higher risk for major bleeding and gastrointestinal bleeding than those who take warfarin. The findings indicate that more caution is needed when prescribing dabigatran to certain high-risk patients, said researchers...Read more

ICU Management

Icu-volume-14-issue-3-autumn-2014

2014 24 Sep

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