Search Tag: bleeding
European Guidelines: Management of Bleeding, Coagulopathy Following Trauma
2023 07 Mar
According to the Global Burden of Diseases, Injuries, and Risk Factors Study, trauma accounted for 8% of total deaths annually. Among adolescents aged 10-24 years, road injuries, self-harm, and interpersonal violence are the top causes of disability-adjusted life-years, and road injuries are ranked first in the 25-49 year age group. Post-traumatic... Read more
Treatment Options for Factor-Xa Inhibitor-Related Bleeding
2019 26 Sep
Specific treatment options for factor Xa inhibitor-related bleeding, focusing on drugs like rivaroxaban, apixaban, and edoxaban. Non-vitamin K oral anticoagulants (NOACs/DOACs) are direct reversible inhibitors of factor Xa. These drugs are also reversible inhibitors versus warfarin or other vitamin K antagonist that are used in Europe. Anticoagulants... Read more
European guideline on managing post-traumatic bleeding: 5th edition
2019 02 Apr
An updated guideline on the management of significant bleeding and coagulopathy following major trauma has been released by the pan-European, multidisciplinary Task Force for Advanced Bleeding Care in Trauma. The document, published in the journal Critical Care, includes recommendations intended to guide the management of patients during the early... Read more
Use of aspirin in individuals without cardiovascular disease
2019 24 Jan
Cardiovascular disease continues to be a leading killer in the US as well as around the globe. While the number of deaths from cardiovascular disease has reduced over the years, deaths from stroke and myocardial infarction have plateaued in the US. Since the prevalence of cardiovascular disease continues to be both a health and economic burden,... Read more
Is pre-hospital coagulation management in trauma feasible?
2018 01 Jun
Coagulation management remains a formidable challenge in severely bleeding trauma patients. A strong rationale suggests starting treatment of trauma-induced coagulopathy in the pre-hospital phase. The burden of trauma is increasing worldwide, particularly in less well-resourced nations. There are an estimated 5 million deaths per year, more... Read more
Are newer anticoagulants safer than warfarin?
2018 03 Apr
A new study compared outcomes among patients with atrial fibrillation hospitalised for bleeding after starting anticoagulation (warfarin, dabigatran, or rivaroxaban). Results show rivaroxaban and dabigatran were associated with shorter hospitalisations; however, there were no differences in 30- and 90-day mortality. These findings suggest bleeding... Read more
Improving Treatment of Life-Threatening Bleeding
2015 17 May
U.S. researchers have successfully field tested a system that analysed patient vital signs during emergency transport, finding that it could detect those with life-threatening bleeding before they arrive at the hospital, potentially saving lives. The study, published in the journal Shock , was conducted by researchers from Massachusetts General Hospital... Read more
Heart Catheterisation: Arm Is Safer Access Point
2015 20 Mar
A new study shows that patients with acute coronary syndrome undergoing coronary angiogram, a procedure used to assess blockages in the heart's arteries, had a significantly lower risk of major bleeding and death if their interventional cardiologist accessed the heart through an artery in the arm rather than the groin. Researchers said the results,... Read more
Anticoagulant Bivalirudin May Improve Outcomes Compared to Heparin
2015 17 Mar
According to a study published in JAMA, patients who experienced a heart attack and underwent a percutaneous coronary intervention (PCI) show a decrease in adverse clinical events when they were given anticoagulant bivalirudin following the procedure. Compared to heparin alone or heparin plus tirofiban, bivalirudin resulted in a reduction in adverse... Read more
Findings Enable Better Management of Anticoagulant-related Bleeding
2015 26 Feb
According to a study published in JAMA, patients with oral anticoagulation-associated intracerebral haemorrhage, reversal of international normalised ratio (INR) below a certain level within 4 hours and systolic blood pressure less than 160 mm Hg at 4 hours were associated with lower rates of haematoma enlargement, and resumption of anticoagulant therapy... Read more