Search Tag: bacterial resistance

ICU Management

What's the effective antibiotic dosing in critically ill patients?

2017 28 Nov

Mortality due to severe infections in the intensive care unit (ICU) remains high despite recent therapeutic advancements. It is believed that ICU pathogens are relatively different from those in the general wards as they commonly have reduced antibiotic susceptibility. However, despite profound physiological and pharmacokinetic differences to the non-critically... Read more

ICU Management

Treating Pneumonia with Antibiotics

2015 03 Apr

According to the results of a new study published in the New England Journal of Medicine and carried out by researchers at the University Medical Center Utrecht (UMCU), patients with pneumonia can be treated with most common antibiotics which are as effective as the more expensive alternatives. Despite the fact that there are various types of antibiotics... Read more

ICU Management

New Software Predicts Superbugs' Countermoves to New Drugs

2015 05 Jan

In the fight against drug-resistant bacteria, new drugs are urgently needed, but so are ways to maximise the effective lifespan of these drugs. Researchers at Duke University in the U.S. have developed open-source software that can predict a constantly-evolving infectious bacterium's counter-moves to a new drug before the drug is tested on patients.... Read more

ICU Management

Emerging Antiseptic Resistance in ICUs

2014 17 Aug

According to a recent study published in Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America, bacteria that cause life-threatening bloodstream infections in critically ill patients may be growing increasingly resistant to chlorhexidine gluconate (CHG), a common hospital antiseptic. The use... Read more