Search Tag: antibiotics

ICU Management

Antibiotic timing and administration in the ED

2019 01 May

Antibiotics are often prescribed in the emergency department (ED) to patients with suspected infection before any definitive diagnosis can be made. However, amidst increasing antibiotic resistance, their use should be limited to those at high risk of infection or further clinical deterioration. Current tools to aid clinical decision-making include... Read more

ICU Management

Optimising beta-lactam treatment in the ICU - expert consensus

2019 03 Apr

The French Society of Pharmacology and Therapeutics (SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (SFAR) have released guidelines on the optimisation of beta-lactam treatment in intensive care unit (ICU) patients. The two groups strongly recommend the use of personalised dosing, continuous or prolonged infusion and therapeutic... Read more

ICU Management

Results of the ABATE infection trial

2019 14 Mar

According to results of the ABATE infection trial, daily bathing with an antiseptic soap, plus nasal ointment for patients with prior antibiotic-resistant bacteria reduced hospital-acquired infections among patients with central venous catheters and other devices.   The ABATE infection trial included 340,000 patients from 53 hospitals. The study... Read more

ICU Management

Highlights from the I-I-I Blog

2018 16 Oct

(I expert, I question, I answer)  Have you got something to say? Visit  https://healthmanagement.org/c/icu/list/blog  or contact [email protected] Jean Baptiste Lascarrou Medical Intensive Care Unit, Nantes University Hospital, France @jblascarrou Epinephrine for out-of-hospital cardiac arrest “Epinephrine... Read more

ICU Management

Improving antibiotic initiation for sepsis, pre-hospital

2018 13 Sep

Sepsis is a common and costly condition encountered by pre-hospital and emergency department (ED) clinicians. Early antibiotics improve outcomes for septic patients. Researchers from Intermountain Medical Center in Utah led a study to investigate the relationship between septic patients’ pre-hospital level of care and ED door-to-antibiotic time. ... Read more

ICU Management

2018 19 Jun

Medical decision-making about antibiotic use in critically ill patients is challenging and complex. The need for antibiotic stewardship requires judicious prescription and choice of antimicrobials, as the need for effective therapy has to be put in balance with the need to limit undue selection pressure, and all this must be done in a context of... Read more

ICU Management

Results of antimicrobial stewardship programme implementation in multidisciplinary hospital

2018 01 Jun

The interventional single-centre with historical control study was conducted in a 600-bed multidisciplinary hospital to evaluate 4 years’ results of an antimicrobial stewardship programme. We found a significant reduction in average duration of courses of antimicrobial therapy, length of stay of patients with infection in ICU, mortality in patients... Read more

ICU Management

2018 26 Mar

The Surviving Sepsis Campaign recommends starting empiric broad-spectrum antibiotics in the initial management of patients with severe sepsis and septic shock (Rhodes et al. 2017). As a consequence, many patients receive unnecessary antibiotics, exposing them to adverse events, while others might be undertreated in spite of broad-spectrum therapy... Read more

ICU Management

New way to fight sepsis: rev up patients' immune systems

2018 13 Mar

People especially those with critical illness develop sepsis when an infection triggers an overwhelming immune response, ultimately wreaking havoc on the immune system. Traditional approaches to sepsis therapy do not address the critical problem of patients' severely compromised immune systems. Now, a clinical trial demonstrates that a drug that revs... Read more