Search Tag: antibiotics

ICU Management

Antibiotic Delay Intervals, Mortality Among Patients With Suspected Sepsis

2021 27 Apr

Timely delivery of antibiotics is a major cornerstone of sepsis therapy. Clinical evidence suggests that every one-hour delay in antibiotics after emergency department (ED) triage or the onset of organ dysfunction or shock could result in a 3-7% increase in the odds of a poor outcome. The Surviving Sepsis Campaign (SSC) guidelines recommend antibiotic... Read more

ICU Management

Biomarker-Guided Antibiotic Stewardship in Suspected Ventilator-Associated Pneumonia

2019 15 Dec

Ventilator-associated pneumonia carries enormous morbidity and mortality, including prolonging hospital stay and increasing the cost of healthcare. In most cases, ventilator-associated pneumonia occurs without any specific signs or symptoms. Making an accurate diagnosis is often difficult. Unlike the past, the administration of empirical antibiotics... Read more

ICU Management

Procalcitonin-Guided Antibiotic Therapy in Severely Critically Ill Patients

2019 30 Aug

The controversy surrounding the efficacy of the blood infection biomarker, procalcitonin (PCT), for guidance in acute infections and sepsis treatment remains. PCT is a calcitonin precursor produced by epithelial cells when infected with bacteria and has been identified as a marker due to the protein levels’ variation upon infection initiation and cessation.... Read more

ICU Management

Antibiotic timing and administration in the ED

2019 01 May

Antibiotics are often prescribed in the emergency department (ED) to patients with suspected infection before any definitive diagnosis can be made. However, amidst increasing antibiotic resistance, their use should be limited to those at high risk of infection or further clinical deterioration. Current tools to aid clinical decision-making include... Read more

ICU Management

Optimising beta-lactam treatment in the ICU - expert consensus

2019 03 Apr

The French Society of Pharmacology and Therapeutics (SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (SFAR) have released guidelines on the optimisation of beta-lactam treatment in intensive care unit (ICU) patients. The two groups strongly recommend the use of personalised dosing, continuous or prolonged infusion and therapeutic... Read more

ICU Management

Results of the ABATE infection trial

2019 14 Mar

According to results of the ABATE infection trial, daily bathing with an antiseptic soap, plus nasal ointment for patients with prior antibiotic-resistant bacteria reduced hospital-acquired infections among patients with central venous catheters and other devices.   The ABATE infection trial included 340,000 patients from 53 hospitals. The study... Read more

ICU Management

Highlights from the I-I-I Blog

2018 16 Oct

(I expert, I question, I answer)  Have you got something to say? Visit  https://healthmanagement.org/c/icu/list/blog  or contact [email protected] Jean Baptiste Lascarrou Medical Intensive Care Unit, Nantes University Hospital, France @jblascarrou Epinephrine for out-of-hospital cardiac arrest “Epinephrine... Read more