Search Tag: adrenaline

ICU Management

2018 27 Aug

Insights from the PARAMEDIC2 trial and future improvements Perkins et al. have advanced the long-awaited PARAMEDIC2 trial (Perkins et al. 2018). They deserve to be congratulated for such a well-interpreted and well-designed contribution. The study’s two main outcomes are as follows: the Epinephrine group had a significantly improved inpatient survival... Read more

ICU Management

PARAMEDIC2: Is epinephrine a safe and effective treatment for cardiac arrest?

2018 24 Jul

In addition to early initiation of cardiopulmonary resuscitation (CPR), treatment strategies for out-of-hospital cardiac arrest have included the use of various drugs, but there is limited evidence that such medications are effective. Results of the  clinical trial (Pre-hospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug... Read more

ICU Management

Better Training Tools to Combat Life-threatening Allergic Reactions

2015 04 Jul

The European Medicines Agency (EMA) has recommended the introduction of more effective educational material to promote appropriate use of adrenaline auto-injectors. The move came following concerns that currently available devices may deliver adrenaline under the skin instead of into a muscle, hence delaying response to treatment. Adrenaline auto-injectors... Read more

Cardiology Management

Cardiac Arrest: Adrenaline Questioned

2014 17 Aug

Over the past decade several scientists have suggested that adrenaline, used for more than fifty years as a key part of resuscitation, may actually do more harm than good. This is based on the evidence that adrenaline may damage the brain by reducing blood supply to the head and may in fact diminish the patient's chances of survival. This is a definite... Read more