Search Tag: Vitamin C

ICU Management

#LIVES2019: Vitamin C for Sepsis

2019 04 Oct

Dr. Alpha A. Fowler of Virginia Commonwealth University presented findings from the CITRIS-ALI trial that studied the role of vitamin C in patients with septic ARDS. The findings were presented @ESICM in Berlin and have just been published in JAMA.  The CITRIS-ALI randomised trial addressed the use of high dose intravenous vitamin C to study... Read more

ICU Management

Vitamin C Drug Cocktail for Sepsis

2019 09 Jul

The combination of intravenous vitamin C, corticosteroids and thiamine has been made famous by Dr. Paul Marik, M.D. for the treatment of sepsis in critically ill patients. The ‘Marik protocol’, also termed HAT (Hydrocortisone, Ascorbic acid, Thiamine), has however come under criticism regarding the lack of evidence. Dr. Marik of Sentara Norfolk... Read more

ICU Management

Stronger evidence for vitamin C use in sepsis treatment

2018 17 Oct

A new meta-analysis reveals a positive correlation between incorporating vitamin C in the treatment of sepsis and favourable patient outcomes. Results of the meta-analysis showed a marked reduction in mortality and duration of vasopressor administration in the group with the use of vitamin C, despite varying degrees of statistical significance between... Read more

ICU Management

Vitamin C in Severe Sepsis Treatment

2017 17 Apr

A new study reported in the journal CHEST demonstrates the beneficial effects of high-dose intravenous vitamin C in reducing mortality in patients with severe sepsis. However, an Editorial published in the same issue of CHEST, calls for more studies to determine optimal dose of vitamin C in the critically ill population. See Also : Albumin Administration... Read more

Cardiology Management

Vitamin C Reduces Risk of Cardiovascular Disease, Early Death

2015 12 Jul

According to new research from the University of Copenhagen and Herlev and Gentofte Hospital, high concentrations of vitamin C in the blood from the intake of fruit and vegetables are associated with a reduced risk of cardiovascular disease and early death. The study has been published in the  American Journal of Clinical Nutrition. It is a well-known... Read more