Search Tag: PCT
2020 14 Sep
Professor Michael Mansour is a physician-scientist with a research concentration in immune responses against invading pathogens. He attends on the Clinical Transplant Infectious Diseases and Immunocompromised Host Service at the Massachusetts General Hospital - Division of Infectious Diseases, where he cares for solid and stem cell transplant recipients...Read more
2020 13 Jun
Sepsis biomarkers have an important role in the diagnosis, prognosis, and treatment of sepsis management. If timely and accurate information about biomarkers becomes available, the physician can not only make better therapeutic choices but also monitor the efficacy of the intervention in progress and adjust it accordingly. In a previous review...Read more
2019 30 Aug
The controversy surrounding the efficacy of the blood infection biomarker, procalcitonin (PCT), for guidance in acute infections and sepsis treatment remains. PCT is a calcitonin precursor produced by epithelial cells when infected with bacteria and has been identified as a marker due to the protein levels’ variation upon infection initiation and cessation....Read more
2018 06 Feb
Using biomarkers as a guide to tailor the duration of antibiotic treatment in respiratory infections is an attractive hypothesis assessed in several studies. However, after more than a decade of randomised controlled trials on procalcitonin (PCT)-guided antibiotic treatment, the evidence favouring PCT use is still less than compelling due to limitations...Read more