Search Tag: ARDS
ARDS reclassification - the debate continues
2018 15 May
A new analysis of data from patients enrolled in high-quality ARDSnet trials showed no difference between patients with moderate-severe and mild-moderate ARDS in terms of mortality, even though there were differences in rapid resolution of ARDS, ventilator-free days and ICU-free days. The research is published online in Annals of the American Thoracic... Read more
CO2 in the critically ill
2018 16 Mar
CO2 exerts potent effects on lung biology that could be clinically relevant in critically ill patients, in particular those with acute respiratory distress syndrome (ARDS). The impact of hypercapnia on outcome in these patients is yet to be determined.The physiological effects of hypercapnia are increasingly well understood, but the literature remains... Read more
ARDS, delirium and antipsychotic use reviewed
2018 21 Feb
Acute respiratory distress syndrome (ARDS) often requires prolonged and complicated hospital courses putting patients at risk for intensive care unit (ICU) delirium. Antipsychotics are prescribed to decrease the severity and duration of ICU delirium; however, these drugs are associated with many adverse effects including respiratory failure. "Given... Read more
Managing ARDS in traumatic brain injury
2018 15 Jan
Traumatic brain injury (TBI) patients frequently suffer from lung complications and acute respiratory distress syndrome (ARDS), which is associated with poor clinical outcomes. However, there are inadequate data addressing the safety or efficacy of ventilator strategies used in ARDS in adult patients with TBI, says an article published in Journal of... Read more
Making mechanical ventilation safe for ARDS
2018 08 Jan
The acute respiratory distress (ARDS) lung is usually characterised by a high degree of inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations, ranging from completely gasless regions, up to hyperinflated areas, explain Luciano Gattinoni, Tommaso Tonetti and Michael Quintel in an article published in the journal Critical... Read more
Can we improve the reliability of ARDS diagnosis?
2018 08 Jan
Failure to reliably diagnose ARDS, or acute respiratory distress syndrome, could lead to underrecognition and undertreatment in clinical practice. New research shows the reliability of the Berlin ARDS definition is "moderate," driven primarily by differences in chest imaging interpretation. The study is in press in the journal CHEST.The 2012 revision... Read more
After 50 years, ARDS stuck in the past?
2017 14 Nov
The acute respiratory distress syndrome (ARDS) was first reported in 1967. Upon the occasion of its 50th birthday, ARDS is due for a midlife crisis, says Dr. Robert P. Dickson, of the Division of Pulmonary and Critical Care Medicine, University of Michigan Health System. "In our era of molecular medicine, ARDS seems a bit stuck in the past," he writes... Read more
Are lung recruitment manoeuvres beneficial to ARDS patients?
2017 01 Nov
Previous research suggests that lung recruitment manoeuvres (LRMs) may prevent ventilator-induced lung injury and improve survival in patients with acute respiratory distress syndrome (ARDS). Now a new systematic review indicates that LRMs in combination with a higher positive end-expiratory pressure (PEEP) ventilation strategy reduce mortality. However,... Read more
LIVES 2017: Lack of severe hypoxaemia most common reason not to prone
2017 05 Oct
Despite proven benefits of proning patients with ARDS (Guérin et al. 2013), patients with ARDS are seldom put in prone position. A one-day prevalence study of prone positioning in ARDS patients, organised by the European Society of Intensive Care Medicine (ESICM) Acute Respiratory Failure Section, found low rates of proning, similar to those in found... Read more