Search Tag: ARDS
Precision Therapies for Heterogeneous ARDS Patients
2021 20 Jul
ARDS is a heterogeneous syndrome rather than a distinct disease. It is this heterogeneity that often makes it difficult to study treatments for patients with ARDS. Literature on ARDS is rife with clinical trials that do not show any mortality benefit. Recent evidence suggests different sub-phenotypes within the heterogeneous patient population.... Read more
Association of Higher vs Lower PEEP on Mortality
2021 19 Jul
Mechanical ventilation is a life-saving strategy for critically ill patients. However, it can promote and/or exacerbate lung injury through several mechanisms, including alveolar overdistension and repetitive opening and closing of the alveoli and small airways. Positive end-expiratory pressure (PEEP) has been employed to prevent end-expiratory alveolar... Read more
Selection Criteria for Lung Transplantation in COVID-19 Patients
2021 06 Apr
In May 2020, a team led by thoracic surgeon Konrad Hoetzenecker of the Department of Surgery of MedUni Vienna and Vienna General Hospital performed a lung transplant on a 44-year-old patient who had been seriously ill with COVID-19. She thus became the first patient in Europe to receive a lung transplant for this indication. The Vienna lung transplantation... Read more
Corticosteroid Treatment in ARDS
2021 30 Mar
Acute respiratory distress syndrome (ARDS) is a life-threatening condition that is characterised by bilateral pulmonary infiltrates on chest imaging and refractory hypoxaemia. ARDS is common in critically ill patients in ICUs and is associated with significant mortality. Findings from a recent study show that approximately 10% of ICU patients suffered... Read more
How Should We Manage Sedation in Critically-Ill COVID-19 Patients?
2021 22 Feb
Clinical Practice Guidelines The Choosing Wisely top five guidelines published a few years ago by the Chest Association of Physicians, the American Thoracic Society, the Society of Critical Care Medicine, and the American Association of Critical Care Nurses state that mechanically ventilated patients should not be deeply sedated without a specific... Read more
Important Questions Answered
2021 22 Feb
During the question/answer session, Prof Vito Marco Ranieri discussed some important questions with Prof Salvatore Maurizio Maggiore and Prof Boris Jung regarding sedation regimen, respiratory muscle paralysis, sedation in COVID-19 patients specifically and how it is different from other regular ICU patients. Ranieri: What is your opinion... Read more
Prone Position in Awake, Non-Intubated Patients with ARDS: From Physiology to the Bedside
2021 22 Feb
Prone position (PP) in awake, non-intubated patients with respiratory failure is a physiology-based ventilatory strategy that improves oxygenation and may decrease the need for intubation and invasive mechanical ventilation (IMV). Introduction During the pandemic caused by the SARS-CoV-2 virus, which produces coronavirus disease... Read more
Optimising Patient Care During COVID-19: The Four Ps
2021 31 Jan
The COVID-19 pandemic has had a significant impact on ICUs around the world. Most healthcare systems were prepared to handle natural disasters or accidents, but as we have all witnessed, they were unprepared to handle the massive influx of patients during the COVID-19 crisis. Last year was quite a challenge for healthcare providers around the world,... Read more
Do We Need to Diagnose ARDS?
2020 19 Oct
Acute respiratory distress syndrome (ARDS) is the clinical expression of acute, non-haemodynamic lung oedema. It is typically diagnosed by hypoxaemia, and bilateral lung infiltrates in the absence of increased capillary hydrostatic pressure. ARDS represents nearly a quarter of the ICU patients who require mechanical ventilation. There is significant... Read more