Search Tag: AKI

ICU Management

AKI may indicate more serious systemic disease

2018 30 Jan

Most cases of acute kidney injury (AKI) represent a manifestation of a system-wide disease, which should be addressed in all patients with an elevated serum creatinine. "Acute kidney injury should most often be seen not as a primary disease entity but a marker of a potentially serious, underlying systemic disease; the kidney may be just an innocent... Read more

ICU Management

Managing renal replacement therapy in AKI patients

2018 23 Jan

It is estimated that 22–57% of critically ill patients develop acute kidney injury (AKI) during their hospitalisation. The increasing incidence of AKI has the immediate effect of a growing need for renal replacement therapy (RRT). However, evidence on how to manage RRT in critically ill patients with AKI remains limited because of ambiguous study results... Read more

ICU Management

Study: AKI alerts associated with lower mortality, LOS

2017 22 Nov

A clinical decision support system (CDSS) that monitors blood creatinine levels in hospitalised patients to alert physicians to potential acute kidney injury (AKI) was associated with a small but significant reduction in mortality and hospital length of stay (LOS), according to research from the University of Pittsburgh and UPMC published in the Journal... Read more

ICU Management

Study: AKI alerts associated with lower mortality, LOS

2017 02 Nov

A clinical decision support system (CDSS) that monitors blood creatinine levels in hospitalised patients to alert physicians to potential acute kidney injury (AKI) was associated with a small but significant reduction in mortality and hospital length of stay (LOS), according to research from the University of Pittsburgh and UPMC published in the Journal... Read more

ICU Management

Biomarkers for Acute Kidney Injury

2016 30 May

Where Are We Now? Acute kidney injury (AKI) has been recognised as a major public health problem. It affects >50% of patients in the Intensive Care Unit (ICU) and is associated with serious short- and long-term complications, premature death and high financial healthcare costs (Mehta et al. 2015; Hoste et al. 2015; Lewington et al. 2013). The consensus... Read more

ICU Management

Early Diagnosis and Prediction of Acute Kidney Injury

2016 30 May

penKid – A Dynamic Inflammation-Independent Biomarker Of Kidney (Dys)function Early recognition and close monitoring of acute kidney injury (AKI) is vital in the ICU, given AKI’s high prevalence and effect on length of stay and risk of re-hospitalisation and death (McCullough et al. 2013). As more becomes known about biomarkers, intensivists need... Read more

ICU Management

Can RIFLE Urine Output Criteria Predict Contrast-Associated Nephropathy?

2016 10 May

A study that assessed the predictive value of the Risk of renal dysfunction, Injury to the kidney, Failure of kidney function, Loss of kidney function and End-stage renal disease (RIFLE) urine output criteria on contrast-induced nephropathy in critically ill patients found its predictive value to be low, which limits its use for assessing the effects... Read more

ICU Management

Protocol for Identifying Patients at Risk of AKI

2015 08 Nov

A new streamlined approach for early detection and treatment of acute kidney injury (AKI) has reduced mortality rates by 23 percent and hospital length of stay by 13 percent, according to a pilot study presented at ASN Kidney Week 2015 in San Diego. AKI is a common condition that affects 21 percent of hospitalised adults and 33 percent of hospitalised... Read more

ICU Management

Fluid Therapy: Buffered Crystalloids No Better Than Saline

2015 08 Oct

Use of a buffered crystalloid for fluid therapy, compared with saline, did not reduce the incidence of acute kidney injury or failure for intensive care unit (ICU) patients, according to new research presented at the 28th annual congress of the European Society of Intensive Care Medicine. The findings are also published in JAMA . Although 0.9 percent... Read more

ICU Management

Global Study: 65% of AKI Cases Are Community Acquired

2015 16 Mar

The International Society of Nephrology (ISN) has presented the findings of a new global study on acute kidney injury (AKI), seen by experts as a key step forward in their efforts to eliminate preventable deaths from the condition by 2025 ('0by25 Initiative'), at its annual meeting held in Cape Town, South Africa. AKI is a worldwide problem, killing... Read more