Metabolism in Cancer and Stromal Cells

Metabolism in Cancer and Stromal Cells
The metabolism of cancer cells and recently also of stromal cells (endothelial cells, immune cells, fibroblasts) have emerged as critical hallmark in the (patho)physiology of organs in healthy and diseased tissue. Evidence indicates that metabolism not only co-determines the differentiation and function of cells, but it also contributes to the pathogenesis of cancer, diabetes and inflammatory diseases. With this international meeting we will focus on how cancer and stromal cells metabolically communicate and how their specific metabolism impacts disease development and progression. These insights into cellular metabolism also offer novel therapeutic opportunities for malignant, metabolic, or inflammatory disease.

This meeting will bring together researchers from cancer metabolism and stromal cell metabolism fields. Renowned speakers will provide a broad view on metabolic regulation, the link between signaling and metabolism as well as the intercellular crosstalk. This event will provide an opportunity to discuss the latest findings in those fields. These discussions will stimulate new ideas and impact the field by introducing novel concepts and experimental approaches.


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General Info

Conference Summary

At this international meeting in Belgium, renowned scientists focus on how cancer and stromal cells metabolically communicate and how their specific metabolism impacts disease development and progression.

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Leuven, Brussel

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Poster abstracts for Metabolism in Cancer and Stromal Cells

All oral presenters will be informed on July 10 (Late submissions for poster presentations will be considered until July 31)

Abstract submission closing date:
Friday, 31 July, 2015
Submit abstract
PARTNERS:
© SelectScience 2015

Computational and Structural Biotechnology Journal

Frontiers Media S.A.

Pharmaceutical Tech

Registration Details

Registration until Monday, 3 August, 2015
PhD student € 250,00
VIB - PhD student
VIB - Academic € 275,00
Academic € 350,00
Industry € 425,00
Click to register here.

Programme Details

Tuesday September 8, 2015
13:00 - 14:15 Registration
14:15 - 17:55 Session 1: Cancer and Autoimmune Diseases
14:15 - 14:30 Welcome
Peter Carmeliet, VIB Vesalius Research Center, KU Leuven, BE
14:30 - 15:30 Regulation of cell metabolism to support tumor growth
Matt Vander Heiden, Koch Institute for Integrative Cancer Research, MIT, US
15:35 - 16:10 mTOR signaling in lymphocyte homeostasis and tumorigenesis
Hongbo Chi, St. Jude Children’s Research Hospital, US
16:10 - 16:40 Coffee Break
16:40 - 17:15 Exploiting the Metabolic Flexibility of Th17 Cells for the treatment of Autoimmunity and Cancer Gary Glick, University of Michigan, US
17:15 - 17:35 Short Talk Presenter selected from abstracts
17:35 - 17:55 Short Talk Presenter selected from abstracts
18:15 - 20:00 Reception
Wednesday September 9, 2015
09:00 - 12:40 Session 2: Angiogenesis and Cardiovascular Diseases
Keynote
09:00 - 10:00 Angiogenesis revisited: endothelial metabolism as a target?
Peter Carmeliet, VIB Vesalius Onderzoekscentrum, KU Leuven, BE
10:00 - 10:35 Metabolic control of lymphatic development
Michael Simons, Yale University, US
10:35 - 11:05 Coffee break
11:05 - 11:40 Metabolic checkpoints during vascular growth and quiescence
Michael Potente, Max Planck Institute for Heart and Lung Research, DE
11:40 - 12:15 PGC-1 and endothelial metabolism
Zolt Arany, University of Pennsylvania, US
12:15 - 12:35 Regulation of endothelial metabolism by laminar shear stress
Reinier Boon, Goethe-University Frankfurt am Main, DE
12:40 - 13:40 Lunch
13:40 - 15:10 Poster session 1
15:30 - 18:40 Session 3: Cancer and Mitochondrial Metabolism
15:30 - 16:05 How mitochondrial metabolism leads to ROS production
Mike Murphy, Cambridge, UK
16:05 - 16:40 Tricarboxylic acid cycle metabolism in cells
Sarah-Maria Fendt, VIB Vesalius Research Center, KU Leuven, BE
16:40 - 17:10 Coffee Break
17:10 - 17:45 Fatty acid metabolism in cancer cells: Are we looking at the right pathway?
Karsten Hiller, University of Luxembourg, LU
17:45 - 18:20 VEGF blockade elicits a stable metabolic shift in tumor cells
Stefano Indraccolo, Istituto Oncologico Veneto-IRCCS, IT
18:20 - 18:40 Short Talk Presenter selected from abstracts
19:30 - 22:30 Conference Dinner
Thursday September 10, 2015
09:00 - 12:00 Session 4: Stromal Cell Metabolism
09:00 - 09:35 Macrophage metabolism in hypoxia: implications for tumor angiogenesis
Max Mazonne, VIB Vesalius Research Center, KU Leuven, BE
09:35 - 10:10 Fueling T cell activation and anti-tumor immunity
Jeff Rathmell, Duke University School of Medicine, US
10:10 - 10:40 Coffee break
10:40 - 11:15 Metabolic adaptation: implications for immunity
Russel Jones, McGill University, US
11:15 - 11:35 Short Talk Presenter selected from abstracts
11:35 - 11:55 Short Talk Presenter selected from abstracts
12:00 - 13:00 Lunch
13:00 - 14:30 Poster session 2
14:30 - 18:00 Session 5: Metabolism in Complex Diseases Keynote
14:30 - 15:30 Metabolic Adaptations in Renal Cancer
Celeste Simon, University of Pennsylvania School of Medicine, US
15:30 - 16:05 Mitochondria, Metabolism and the Determination of Cell
Fate Kris Olson, University of Utah, US 16:05 - 16:35 Coffee break
16:35 - 17:10 Obesity, Metabolism and Cancer: Mechanistic Lessons from Transdisciplinary Studies
Stephen Hursting, UNC School of Medicine, US
17:10 - 17:45 Metabolism bottom-up: a haystack of needles
Nicola Zamboni, ETH Zürich, CH
17:45 - 18:00 Closing remarks



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